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Brief Communications

The Septate Junction Protein Caspr Is Required for Structural Support and Retention of KCNQ4 at Calyceal Synapses of Vestibular Hair Cells

Aurea D. Sousa, Leonardo R. Andrade, Felipe T. Salles, Anilkumar M. Pillai, Elizabeth D. Buttermore, Manzoor A. Bhat and Bechara Kachar
Journal of Neuroscience 11 March 2009, 29 (10) 3103-3108; https://doi.org/10.1523/JNEUROSCI.4868-08.2009
Aurea D. Sousa
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Leonardo R. Andrade
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Felipe T. Salles
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Anilkumar M. Pillai
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Elizabeth D. Buttermore
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Manzoor A. Bhat
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Bechara Kachar
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.4868-08.2009
PubMed 
19279247
Published By 
Society for Neuroscience
History 
  • Received October 9, 2008
  • Revision received January 9, 2009
  • Accepted February 2, 2009
  • First published March 11, 2009.
  • Version of record published March 11, 2009.
Copyright & Usage 
Copyright © 2009 Society for Neuroscience 0270-6474/09/293103-06$15.00/0

Author Information

  1. Aurea D. Sousa1,
  2. Leonardo R. Andrade1,2,
  3. Felipe T. Salles1,
  4. Anilkumar M. Pillai3,
  5. Elizabeth D. Buttermore3,
  6. Manzoor A. Bhat3, and
  7. Bechara Kachar1
  1. 1Laboratory of Cell Structure and Dynamics, National Institute on Deafness and Other Communication Disorders–National Institutes of Health, Bethesda, Maryland 20892-8027,
  2. 2Institute of Biomedical Science, Center of Health Sciences, Federal University of Rio de Janeiro, 21941-590, Rio de Janeiro, Rio de Janeiro, Brazil, and
  3. 3Department of Cell and Molecular Physiology, Curriculum in Neurobiology, Neurodevelopmental Disorders Research Center, University of North Carolina–Neuroscience Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599-7545
  1. Correspondence should be addressed to Dr. Bechara Kachar, Laboratory of Cell Structure and Dynamics, National Institute on Deafness and Other Communication Disorders–National Institutes of Health, Building 50, Room 4249, 50 South Drive, Bethesda, MD 20892-8027. kacharb{at}nidcd.nih.gov
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Author contributions

Disclosures

    • Received October 9, 2008.
    • Revision received January 9, 2009.
    • Accepted February 2, 2009.
  • This work was supported by National Institute on Deafness and Other Communication Disorders, Division of Intramural Research, National Institutes of Health (NIH; B.K.), and NIH Grant GM063074 (M.A.B.). We thank Cole Graydon and Drs. Mark Schneider, Stephan Brenowitz, and Ronald Petralia for helpful discussions, and Uri Manor for assistance on statistical analysis of measurements.

  • Correspondence should be addressed to Dr. Bechara Kachar, Laboratory of Cell Structure and Dynamics, National Institute on Deafness and Other Communication Disorders–National Institutes of Health, Building 50, Room 4249, 50 South Drive, Bethesda, MD 20892-8027. kacharb{at}nidcd.nih.gov

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The Journal of Neuroscience: 29 (10)
Journal of Neuroscience
Vol. 29, Issue 10
11 Mar 2009
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The Septate Junction Protein Caspr Is Required for Structural Support and Retention of KCNQ4 at Calyceal Synapses of Vestibular Hair Cells
Aurea D. Sousa, Leonardo R. Andrade, Felipe T. Salles, Anilkumar M. Pillai, Elizabeth D. Buttermore, Manzoor A. Bhat, Bechara Kachar
Journal of Neuroscience 11 March 2009, 29 (10) 3103-3108; DOI: 10.1523/JNEUROSCI.4868-08.2009

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The Septate Junction Protein Caspr Is Required for Structural Support and Retention of KCNQ4 at Calyceal Synapses of Vestibular Hair Cells
Aurea D. Sousa, Leonardo R. Andrade, Felipe T. Salles, Anilkumar M. Pillai, Elizabeth D. Buttermore, Manzoor A. Bhat, Bechara Kachar
Journal of Neuroscience 11 March 2009, 29 (10) 3103-3108; DOI: 10.1523/JNEUROSCI.4868-08.2009
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