Article Information
- Received February 6, 2009
- Revision received April 8, 2009
- Accepted April 9, 2009
- First published May 20, 2009.
- Version of record published May 20, 2009.
Author Information
- Paula J. Brunton1,
- Ailsa J. McKay1,
- Tomasz Ochędalski2,
- Agnieszka Piastowska2,
- Elżbieta Rębas3,
- Agnieszka Lachowicz2,†, and
- John A. Russell1
- 1Laboratory of Neuroendocrinology, Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, United Kingdom, and
- Departments of 2Comparative Endocrinology and
- 3Molecular Neurochemistry, Medical University of Łódź, 91-425 Łódź, Poland
- Correspondence should be addressed to Paula J. Brunton, Centre for Integrative Physiology, Hugh Robson Building, George Square, University of Edinburgh, Edinburgh EH8 9XD, UK. p.j.brunton{at}ed.ac.uk
Author contributions
Disclosures
- Received February 6, 2009.
- Revision received April 8, 2009.
- Accepted April 9, 2009.
-
This work was supported by the Biotechnology and Biological Sciences Research Council, British Council, by Medical University of Łódź Grants 502-19-681 and 502-11-581, and by Ministry of Science and Higher Education Grant N404-1077-33 (Poland). We thank Helen Cameron (University of Edinburgh, Edinburgh, UK) for technical assistance. Undergraduate students Joanne Halfacre, Catherine Harrison, and Stella Howgate assisted in some experiments. Prof. Marcel Karperien and Dr. Jakomijn Hoogendam (University of Leiden, Leiden, The Netherlands) provided the plasmid containing 5α-reductase cDNA, and Prof. Trevor Penning (University of Pennsylvania, Philadelphia, PA) provided the plasmid containing 3α-hydroxysteroid dehydrogenase cDNA. Prof. Vladimir Patchev (Jenapharm, Jena, Germany) gave technical advice on 3α-hydroxysteroid dehydrogenase in situ hybridization. Protein measurements were performed at the Medical University of Łódź. Dr. Martin Simmen and Prof. Gareth Leng (University of Edinburgh) provided expert advice on performing the statistical analyses. This paper is dedicated to the memory of Prof. Agnieszka Lachowicz (1961–2008).
- Correspondence should be addressed to Paula J. Brunton, Centre for Integrative Physiology, Hugh Robson Building, George Square, University of Edinburgh, Edinburgh EH8 9XD, UK. p.j.brunton{at}ed.ac.uk