Article Figures & Data
Figures
- Figure 1.
a, Microphotographs of tyrosine-hydroxylase-stained fibers, in the prelimbic cortex (left column)/infralimbic cortex (right column), for representative rats with bilateral injection of vehicle (SHAM group) or 6-hydroxy-dopamine in the prelimbic cortex (PL group)/infralimbic cortex (IL group). Top, Schematic representation of coronal sections in which photographs were taken (Paxinos and Watson, 1998); scale bar, 100 μm. Orientation of each photograph is from deep (left) to superficial layers (right). b, Quantification of tyrosine hydroxylase-stained fibers (relative to SHAM group, mean + SE) for the PL group (white bars) and the IL group (black bars) in prelimbic and infralimbic cortices. c, Quantification of dopamine-β-hydroxylase-stained fibers (relative to SHAM group, mean + SE) for PL group (white bars) and IL group (black bars) in prelimbic and infralimbic cortices. Dotted lines correspond to baseline levels in SHAM group. *p < 0.05, **p < 0.01.
- Figure 2.
a, Devaluation test. Rates of lever pressing relative to baseline (mean + SE) during the 5 min test after specific-satiety devaluation, for the nondevalued condition (NDev; white bars) and the devalued condition (Dev; black bars) for SHAM, PL, and IL groups. b, Consumption test. Consumption index (mean + SE) during the consumption test, for the nondevalued reward (white bars) and the devalued reward (black bars) for SHAM, PL and IL groups. ***p < 0.001.
- Figure 3.
Contingency degradation. Rates of lever presses relative to baseline (mean + SE) during the 4 d of contingency degradation in the nondegraded condition (NDegr, left) and the degraded condition (Degr, middle) for SHAM, PL, and IL groups. Inset (right) shows the rate of magazine entries relative to baseline (mean of the 4 sessions of contingency degradation procedure + SE) in the degraded condition for SHAM, PL, and IL groups. SNK test: *p < 0.05, **p < 0.01.
- Figure 4.
Schematic representation of infusion sites within the medial prefrontal cortex. a, Open circles: vehicle group. b, Filled circles: flupenthixol group. Outlines of the coronal sections are taken from +3.7 mm to +2.7 mm relative to bregma (Paxinos and Watson, 1998).
- Figure 5.
Contingency degradation. Rates of lever presses relative to baseline (mean + SE) during the 4 d of contingency degradation for VEH and FLU groups. *p < 0.05, **p < 0.01.
