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Chemically Inducible Inactivation of Protein Synthesis in Genetically Targeted Neurons

Hyun-Soo Je, Yuan Lu, Feng Yang, Guhan Nagappan, Jianzheng Zhou, Zhihong Jiang, Kazu Nakazawa and Bai Lu
Journal of Neuroscience 27 May 2009, 29 (21) 6761-6766; DOI: https://doi.org/10.1523/JNEUROSCI.1280-09.2009
Hyun-Soo Je
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Yuan Lu
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Feng Yang
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Guhan Nagappan
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Jianzheng Zhou
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Zhihong Jiang
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Kazu Nakazawa
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Bai Lu
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1280-09.2009
PubMed 
19474302
Published By 
Society for Neuroscience
History 
  • Received March 13, 2009
  • Revision received April 20, 2009
  • Accepted April 23, 2009
  • First published May 27, 2009.
  • Version of record published May 27, 2009.
Copyright & Usage 
Copyright © 2009 Society for Neuroscience 0270-6474/09/296761-06$15.00/0

Author Information

Author contributions

  1. ↵*H.-S.J. and Y.L. contributed equally to this work.

Disclosures

    • Received March 13, 2009.
    • Revision received April 20, 2009.
    • Accepted April 23, 2009.
  • Editor's Note: Toolboxes are intended to briefly highlight a new method or a resource of general use in neuroscience or to critically analyze existing approaches or methods. For more information, see http://www.jneurosci.org/misc/itoa.shtml.

  • This research was supported by the Intramural Research Program of the National Institutes of Health. We thank Drs. Newton Woo, Angela Mabb, Thomas Newpher, and Keri Martinowich for helpful discussions and critical comments on the manuscript, ARIAD Pharmaceuticals for AP20187, and Regeneron Pharmaceuticals for the recombinant BDNF.

  • Correspondence should be addressed to Dr. Bai Lu, Porter Neuroscience Research Center, Laboratory of Cellular and Synaptic Neurophysiology, National Institute of Child Health and Human Development, National Institutes of Health, 35 Lincoln Drive, MSC 3714, Building 35, Room 1C1004 Office, Bethesda, MD 20892-3714. bailu{at}mail.nih.gov

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The Journal of Neuroscience: 29 (21)
Journal of Neuroscience
Vol. 29, Issue 21
27 May 2009
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Chemically Inducible Inactivation of Protein Synthesis in Genetically Targeted Neurons
Hyun-Soo Je, Yuan Lu, Feng Yang, Guhan Nagappan, Jianzheng Zhou, Zhihong Jiang, Kazu Nakazawa, Bai Lu
Journal of Neuroscience 27 May 2009, 29 (21) 6761-6766; DOI: 10.1523/JNEUROSCI.1280-09.2009

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Chemically Inducible Inactivation of Protein Synthesis in Genetically Targeted Neurons
Hyun-Soo Je, Yuan Lu, Feng Yang, Guhan Nagappan, Jianzheng Zhou, Zhihong Jiang, Kazu Nakazawa, Bai Lu
Journal of Neuroscience 27 May 2009, 29 (21) 6761-6766; DOI: 10.1523/JNEUROSCI.1280-09.2009
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