Figure 1.
MBH leucine and KIC injections reduce food intake and body weight in rat and mouse.
a–h
, Cumulative (Cum.) food intake (
a
,
e
), 24 h change in body weight (BW) (
b
,
f
), mean meal size (
c
,
g
), and cumulative meal number (
d
,
h
) in rat (
a–d
, n = 10–12) and mouse (
e–h
, n = 8) following an MBH injection of aCSF, leucine, or KIC (injection design 1). Data are means ± SEM. *p < 0.05 versus aCSF; **p < 0.01 versus aCSF; ***p < 0.001 versus aCSF.