Adult-Born Hippocampal Dentate Granule Cells Undergoing Maturation Modulate Learning and Memory in the Brain

Wei Deng; Michael D. Saxe; Iryna S. Gallina; Fred H. Gage

doi:10.1523/JNEUROSCI.3362-09.2009

Article Information

DOI

https://doi.org/10.1523/JNEUROSCI.3362-09.2009

PubMed

19864566

Published By

Society for Neuroscience

History

Received July 14, 2009
Revision received September 9, 2009
Accepted September 10, 2009
First published October 28, 2009.

Version of record published October 28, 2009.

Author Information

Wei Deng,
Michael D. Saxe,
Iryna S. Gallina, and
Fred H. Gage

Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, California 92037

Correspondence should be addressed to Fred H. Gage at the above address. gage{at}salk.edu

M. D. Saxe's present address: BrainCells Inc., 3565 General Atomics Court, Suite 200, San Diego, CA 92121.

View Full Text

Author contributions

M. D. Saxe's present address: BrainCells Inc., 3565 General Atomics Court, Suite 200, San Diego, CA 92121.

View Abstract

Disclosures

Received July 14, 2009.
Revision received September 9, 2009.
Accepted September 10, 2009.

Funding was provided by a National Institutes of Health Translational Cardiovascular Science and Medicine Training Grant, the Lookout Fund, the McDonnell Foundation, the United States National Institutes of Health (NS-05050217 and NS-05052842), and the National Institute on Aging (AG-020938). We thank Dr. Rüdiger Klein for providing the Nestin promoter/enhancer plasmid, Drs. Sebastian Jessberger, Chunmei Zhao, and James B. Aimone for constructive comments on this manuscript, and Mary Lynn Gage for editorial comments.
Correspondence should be addressed to Fred H. Gage at the above address. gage{at}salk.edu

Statistics from Altmetric.com

Article usage

Select a custom date range for the past year

Article usage: October 2009 to January 2021

	Abstract	Full	Pdf
Oct 2009	581	123	540
Nov 2009	287	366	533
Dec 2009	91	145	182
Total 2009	959	634	1255
Jan 2010	140	202	170
Feb 2010	58	135	131
Mar 2010	45	125	130
Apr 2010	41	107	104
May 2010	29	103	100
Jun 2010	30	88	95
Jul 2010	28	85	86
Aug 2010	38	79	85
Sep 2010	44	81	98
Oct 2010	44	57	68
Nov 2010	43	72	105
Dec 2010	28	47	48
Total 2010	568	1181	1220
Jan 2011	30	43	51
Feb 2011	17	82	47
Mar 2011	53	80	195
Apr 2011	53	61	52
May 2011	45	51	52
Jun 2011	38	43	42
Jul 2011	37	44	38
Aug 2011	25	23	44
Sep 2011	54	44	49
Oct 2011	46	57	43
Nov 2011	49	65	70
Dec 2011	30	57	39
Total 2011	477	650	722
Jan 2012	44	51	45
Feb 2012	40	46	41
Mar 2012	42	57	43
Apr 2012	38	47	34
May 2012	51	45	32
Jun 2012	25	34	30
Jul 2012	41	41	31
Aug 2012	29	25	33
Sep 2012	21	26	39
Oct 2012	52	32	56
Nov 2012	66	24	36
Dec 2012	39	20	24
Total 2012	488	448	444
Jan 2013	27	28	28
Feb 2013	40	40	26
Mar 2013	42	22	42
Apr 2013	81	28	30
May 2013	50	34	38
Jun 2013	30	24	22
Jul 2013	38	26	22
Aug 2013	27	24	23
Sep 2013	26	32	22
Oct 2013	38	26	26
Nov 2013	33	11	21
Dec 2013	22	15	13
Total 2013	454	310	313
Jan 2014	35	19	21
Feb 2014	31	19	18
Mar 2014	39	30	20
Apr 2014	62	28	36
May 2014	35	28	19
Jun 2014	57	23	19
Jul 2014	58	40	14
Aug 2014	21	16	10
Sep 2014	39	30	26
Oct 2014	54	30	21
Nov 2014	43	23	21
Dec 2014	61	21	21
Total 2014	535	307	246
Jan 2015	37	20	19
Feb 2015	37	14	20
Mar 2015	52	46	16
Apr 2015	32	20	15
May 2015	65	15	16
Jun 2015	36	30	32
Jul 2015	45	8	21
Aug 2015	22	11	9
Sep 2015	35	14	10
Oct 2015	44	26	12
Nov 2015	44	29	14
Dec 2015	45	28	15
Total 2015	494	261	199
Jan 2016	50	29	5
Feb 2016	19	20	14
Mar 2016	45	26	24
Apr 2016	40	17	21
May 2016	21	14	13
Jun 2016	26	20	18
Jul 2016	31	16	9
Aug 2016	37	9	10
Sep 2016	38	12	10
Oct 2016	22	16	9
Nov 2016	13	27	18
Dec 2016	3	38	4
Total 2016	345	244	155
Jan 2017	5	29	6
Feb 2017	23	50	14
Mar 2017	15	48	11
Apr 2017	13	39	13
May 2017	25	86	20
Jun 2017	17	33	19
Jul 2017	34	32	10
Aug 2017	10	44	8
Sep 2017	8	26	14
Oct 2017	15	32	16
Nov 2017	18	36	44
Dec 2017	11	22	17
Total 2017	194	477	192
Jan 2018	7	22	8
Feb 2018	2	42	6
Mar 2018	1	46	2
Apr 2018	0	29	4
May 2018	2	42	16
Jun 2018	1	38	13
Jul 2018	9	26	8
Aug 2018	5	34	6
Sep 2018	5	27	9
Oct 2018	5	39	40
Nov 2018	8	29	9
Dec 2018	6	38	17
Total 2018	51	412	138
Jan 2019	7	18	16
Feb 2019	4	16	9
Mar 2019	9	30	20
Apr 2019	9	33	20
May 2019	16	35	28
Jun 2019	4	14	4
Jul 2019	6	22	26
Aug 2019	6	28	14
Sep 2019	7	41	17
Oct 2019	12	76	13
Nov 2019	2	26	8
Dec 2019	4	22	7
Total 2019	86	361	182
Jan 2020	6	34	11
Feb 2020	6	20	33
Mar 2020	5	19	10
Apr 2020	13	30	20
May 2020	3	27	12
Jun 2020	6	17	3
Jul 2020	10	20	25
Aug 2020	9	14	11
Sep 2020	5	39	26
Oct 2020	21	51	21
Nov 2020	17	41	21
Dec 2020	12	65	21
Total 2020	113	377	214
Jan 2021	5	21	6
Total 2021	5	21	6
Total	4769	5683	5286