Article Information
PubMed
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History
- Received September 29, 2009
- Accepted October 12, 2009
- First published November 18, 2009.
- Version of record published November 18, 2009.
Copyright & Usage
Copyright © 2009 Society for Neuroscience 0270-6474/09/2914581-15$15.00/0
Author Information
- Annalisa Scimemi,
- Hua Tian, and
- Jeffrey S. Diamond
- Synaptic Physiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892-3701
- Correspondence should be addressed to either Annalisa Scimemi or Jeffrey S. Diamond, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 35 Convent Drive, Building 35, Room 3C1006-3C1000, Bethesda, MD 20892-3701, scimemia{at}ninds.nih.gov or diamondj{at}ninds.nih.gov
Author contributions
Disclosures
- Received September 29, 2009.
- Accepted October 12, 2009.
-
This work was supported by the National Institute of Neurological Disorders and Stroke (NINDS) Intramural Research Program and Human Frontier Science Program (RGP50/2006). We thank N. C. Danbolt for the EAAC1 antibody, the NINDS EM facility for technical assistance, and D. M. Kullmann and C. J. McBain for comments on this manuscript. Thanks to M. Dittrich for help with the MCell software and M. Beato, K. Paradiso, and A. V. Tzingounis for valuable discussions. A.S. performed electrophysiological recordings, EM analysis, 2P-LSM imaging, diffusion measurements, and modeling. H.T. performed molecular biology experiments. A.S. and J.S.D. designed the research and wrote this manuscript.
- Correspondence should be addressed to either Annalisa Scimemi or Jeffrey S. Diamond, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 35 Convent Drive, Building 35, Room 3C1006-3C1000, Bethesda, MD 20892-3701, scimemia{at}ninds.nih.gov or diamondj{at}ninds.nih.gov