Figure 3.
Activity of a representative single wake/REM sleep active neuron across various sleep–wake behaviors. A–D, The activity of the same neuron is depicted during wake (A), non-REM sleep (B), REM sleep (C), and cataplexy (D). E, F, Rate histograms summarizes the discharge rate (number of spikes/bin; bin width = 500 ms) during wake (E) and REM sleep (F) and demonstrates that this neuron was active during both wake and REM sleep. G, H, Peristimulus/event time histogram summarizes the change in discharge rate (spikes/bin; bin width = 500 ms) of this neuron during transition from cataplexy to wake (G) and from REM sleep to waking (H). As can be seen in G and H, this neuron increased firing from cataplexy (no muscle tone) to waking, but its activity did not change from REM sleep (no muscle tone) to wake. Calibration: 100 μV.