Cover legend: Radial cell end-feet immunostained with nestin in the ventrolateral region of a lumbar spinal cord from a mouse embryo. Yellow traces: Single channel activity recorded in an embryonic lumbar motoneuron (whole cell patch clamp recording; embryonic day 12.5) reflecting spontaneous glycine receptor activation. For more information, see the article by Scain et al. in this issue (pages 390–403).