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Cover ArticleArticles, Cellular/Molecular

Dyrk1A Overexpression Inhibits Proliferation and Induces Premature Neuronal Differentiation of Neural Progenitor Cells

Odessa Yabut, Jason Domogauer and Gabriella D'Arcangelo
Journal of Neuroscience 17 March 2010, 30 (11) 4004-4014; https://doi.org/10.1523/JNEUROSCI.4711-09.2010
Odessa Yabut
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Jason Domogauer
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Gabriella D'Arcangelo
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.4711-09.2010
PubMed 
20237271
Published By 
Society for Neuroscience
History 
  • Received September 22, 2009
  • Revision received January 19, 2010
  • Accepted January 27, 2010
  • First published March 17, 2010.
  • Version of record published March 17, 2010.
Copyright & Usage 
Copyright © 2010 the authors 0270-6474/10/304004-11$15.00/0

Author Information

  1. Odessa Yabut1,2,
  2. Jason Domogauer1, and
  3. Gabriella D'Arcangelo1
  1. 1Department of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, and
  2. 2Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030
  1. Correspondence should be addressed to Dr. Gabriella D'Arcangelo, Department of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ 08854. darcangelo{at}biology.rutgers.edu
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Author contributions

Disclosures

    • Received September 22, 2009.
    • Revision received January 19, 2010.
    • Accepted January 27, 2010.
  • Support for the initial stages of this work was provided by a Basil O'Connor Starter Scholar Research Award from The March of Dimes and National Institutes of Health (NIH) Grant R03 HD39914 from National Institute of Child Health and Human Development (G.D.). Additional support was provided by NIH Grant R01 NS042616 from National Institute of Neurological Disorders and Stroke (G.D.) and a Research Supplement to Promote Diversity in Health-Related Research (O.Y.). We thank the following: A. Renfro-Spelman for assistance with plasmid construction; S. Freemantle, R. Behringer, and D. O'Leary for plasmid constructs; B. Antalffy, J. Zhang, and K. Herrup for technical and scientific advice; C.-C. Huang, C. Ljungberg, and W. Krause for critical reading of this manuscript and helpful discussions; and N. Kane-Goldsmith and the Neuroscience Imaging Facility in the W. M. Keck Center for Collaborative Neuroscience at Rutgers for assistance with confocal microscopy.

  • Correspondence should be addressed to Dr. Gabriella D'Arcangelo, Department of Cell Biology and Neuroscience, Rutgers, The State University of New Jersey, Piscataway, NJ 08854. darcangelo{at}biology.rutgers.edu

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Mar 202534911
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The Journal of Neuroscience: 30 (11)
Journal of Neuroscience
Vol. 30, Issue 11
17 Mar 2010
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Dyrk1A Overexpression Inhibits Proliferation and Induces Premature Neuronal Differentiation of Neural Progenitor Cells
Odessa Yabut, Jason Domogauer, Gabriella D'Arcangelo
Journal of Neuroscience 17 March 2010, 30 (11) 4004-4014; DOI: 10.1523/JNEUROSCI.4711-09.2010

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Dyrk1A Overexpression Inhibits Proliferation and Induces Premature Neuronal Differentiation of Neural Progenitor Cells
Odessa Yabut, Jason Domogauer, Gabriella D'Arcangelo
Journal of Neuroscience 17 March 2010, 30 (11) 4004-4014; DOI: 10.1523/JNEUROSCI.4711-09.2010
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