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Articles, Development/Plasticity/Repair

Protogenin Defines a Transition Stage during Embryonic Neurogenesis and Prevents Precocious Neuronal Differentiation

Yu-Hui Wong, Ai-Chu Lu, Yu-Chiuan Wang, Hsu-Chen Cheng, Celia Chang, Po-Hao Chen, Jenn-Yah Yu and Ming-Ji Fann
Journal of Neuroscience 24 March 2010, 30 (12) 4428-4439; DOI: https://doi.org/10.1523/JNEUROSCI.0473-10.2010
Yu-Hui Wong
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Ai-Chu Lu
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Yu-Chiuan Wang
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Hsu-Chen Cheng
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Celia Chang
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Po-Hao Chen
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Jenn-Yah Yu
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Ming-Ji Fann
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0473-10.2010
PubMed 
20335479
Published By 
Society for Neuroscience
History 
  • Received January 28, 2010
  • Accepted February 13, 2010
  • First published March 24, 2010.
  • Version of record published March 24, 2010.
Copyright & Usage 
Copyright © 2010 the authors 0270-6474/10/304428-12$15.00/0

Author Information

  1. Yu-Hui Wong1,
  2. Ai-Chu Lu1,
  3. Yu-Chiuan Wang1,
  4. Hsu-Chen Cheng3,
  5. Celia Chang1,
  6. Po-Hao Chen1,
  7. Jenn-Yah Yu2, and
  8. Ming-Ji Fann1,2
  1. 1Institute of Neuroscience and
  2. 2Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei 112, Taiwan, and
  3. 3Department of Life Sciences, National Chung Hsing University, Taichung 402, Taiwan
  1. Correspondence should be addressed to Dr. Ming-Ji Fann, Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei 112, Taiwan. mjfann{at}ym.edu.tw
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Author contributions

Disclosures

    • Received January 28, 2010.
    • Accepted February 13, 2010.
  • This research was supported by National Health Research Institutes Grant NHRI-GT-EX89S732C, National Science Council Grant NSC92-2320-B-010-069, the Yen Tjing Ling Medical Foundation, and the Ministry of Education (Aim for the Top University Plan) (M.-J. F.). We thank H.-M. Shih for guidance during the yeast two-hybrid screening, D. L. Turner for the expression vector (pAscl1) and two shRNA vectors (UI4-puro and UI4-GFP), N. Nakatsuji for the pCAG–EYFP–CAG vector, H.-M. Lai for preparing tissue culture reagents, the Developmental Studies Hybridoma Bank for providing monoclonal antibodies, and C.-M. Chen, L.-S. Kao, and C.-Y. Kuan for discussion and critical reading of this manuscript.

  • Correspondence should be addressed to Dr. Ming-Ji Fann, Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei 112, Taiwan. mjfann{at}ym.edu.tw

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Mar 20102445999
Apr 20101136455
May 2010663225
Jun 2010313325
Jul 2010333027
Aug 2010943220
Sep 2010312921
Oct 2010266634
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Dec 2010244024
Total 2010690430349
Jan 2011305124
Feb 2011193523
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Jul 2011203415
Aug 2011362918
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Feb 2012432711
Mar 2012684522
Apr 2012556813
May 2012546619
Jun 2012505915
Jul 2012563314
Aug 201237207
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Total 2012608459161
Jan 2013483916
Feb 2013442711
Mar 2013562814
Apr 2013353614
May 201333368
Jun 2013353110
Jul 201328346
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Sep 2013413013
Oct 2013343712
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Dec 201319228
Total 2013449387136
Jan 201434419
Feb 201426138
Mar 2014532216
Apr 201443129
May 2014312913
Jun 201419263
Jul 201434246
Aug 201419203
Sep 201419225
Oct 201445197
Nov 2014142119
Dec 201418295
Total 2014355278103
Jan 201516226
Feb 201516239
Mar 201519248
Apr 2015131711
May 201512196
Jun 2015292015
Jul 201523123
Aug 2015362212
Sep 201539146
Oct 201530196
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Dec 20152085
Total 201528422195
Jan 201631176
Feb 20162886
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Apr 201642157
May 2016201313
Jun 2016233111
Jul 201630158
Aug 201626135
Sep 201619144
Oct 2016172912
Nov 2016122619
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Total 2016280225126
Jan 20178176
Feb 20179285
Mar 201764013
Apr 201752710
May 201762713
Jun 20173217
Jul 20179286
Aug 20173228
Sep 20174218
Oct 20175154
Nov 20173198
Dec 20175214
Total 20176628692
Jan 201833411
Feb 20184228
Mar 20189223
Apr 20185162
May 20184182
Jun 20187264
Jul 20188192
Aug 20182282
Sep 20186533
Oct 20183493
Nov 20189476
Dec 201811414
Total 20187137550
Jan 20194295
Feb 20195307
Mar 20198293
Apr 201914187
May 20196157
Jun 20198183
Jul 20193209
Aug 20199218
Sep 201914362
Oct 20194237
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Total 20198829580
Jan 20204197
Feb 20203223
Mar 202011238
Apr 20200124
May 20205189
Jun 20200249
Jul 20204175
Aug 202021512
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Total 20205130399
Jan 202193415
Feb 202133012
Mar 202195224
Apr 2021106013
May 20216286
Jun 20215395
Jul 202173013
Aug 202163413
Sep 20215114
Oct 202112825
Nov 202135622
Dec 202123810
Total 202166440162
Jan 20226356
Feb 2022103111
Mar 202215209
Apr 20223668
May 20222115
Total 20223616339
Total349243651765
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The Journal of Neuroscience: 30 (12)
Journal of Neuroscience
Vol. 30, Issue 12
24 Mar 2010
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Protogenin Defines a Transition Stage during Embryonic Neurogenesis and Prevents Precocious Neuronal Differentiation
Yu-Hui Wong, Ai-Chu Lu, Yu-Chiuan Wang, Hsu-Chen Cheng, Celia Chang, Po-Hao Chen, Jenn-Yah Yu, Ming-Ji Fann
Journal of Neuroscience 24 March 2010, 30 (12) 4428-4439; DOI: 10.1523/JNEUROSCI.0473-10.2010

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Protogenin Defines a Transition Stage during Embryonic Neurogenesis and Prevents Precocious Neuronal Differentiation
Yu-Hui Wong, Ai-Chu Lu, Yu-Chiuan Wang, Hsu-Chen Cheng, Celia Chang, Po-Hao Chen, Jenn-Yah Yu, Ming-Ji Fann
Journal of Neuroscience 24 March 2010, 30 (12) 4428-4439; DOI: 10.1523/JNEUROSCI.0473-10.2010
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