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Brief Communications

Motor Sequences and the Basal Ganglia: Kinematics, Not Habits

Michel Desmurget and Robert S. Turner
Journal of Neuroscience 2 June 2010, 30 (22) 7685-7690; https://doi.org/10.1523/JNEUROSCI.0163-10.2010
Michel Desmurget
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Robert S. Turner
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    Figure 1.

    Representative sequences performed by monkey H in the RND preinjection (A), OLRN preinjection (B), and OLRN postinjection (C) conditions. The left and right panels show position and velocity data, respectively. Each sequence component is identified by a different color. Black sections of the velocity curves indicate periods of immobility (velocity <25 mm/s). Left, Continuous arcs in corners indicate positions of the instruction cues. Dotted arcs indicate the peripheral target zones for cursor movements. Right, Dots on the velocity curves indicate the instant of presentation of the instruction cue. Numbers define targets (left) and which target was indicated by each instruction cue (right). The figures are scaled to show the central region of the workspace.

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    Figure 2.

    A, The effects of GPi inactivation on general measures of task performance did not differ between RND and OLRN conditions. Errors rates (iii) are subdivided into the following: P, performance errors; S, OLRN-consistent misdirections in the RND condition; and A, aborted trials. B, Movement kinematics differed across component ranks (C1–C4) and between conditions (RND or OLRN) due to idiosyncratic differences in performance. Inactivation effects did not interact with any rank or condition effects, however. Shown are means (±SD) for 19 injection sessions in two animals. p values summarize results for injection × rank, injection × condition, and injection × rank × condition interactions from a four-way between (animals) × within (injection, condition, rank) ANOVA.

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    Figure 3.

    Representative examples of erroneous predictive responses performed by monkey C during RND trials after one (A), two (B), or three (C) targets followed, by coincidence, the order of the OLRN sequence (1→2→3→4). All three examples are taken from postinjection epochs. The figure follows conventions from Figure 1.

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The Journal of Neuroscience: 30 (22)
Journal of Neuroscience
Vol. 30, Issue 22
2 Jun 2010
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Motor Sequences and the Basal Ganglia: Kinematics, Not Habits
Michel Desmurget, Robert S. Turner
Journal of Neuroscience 2 June 2010, 30 (22) 7685-7690; DOI: 10.1523/JNEUROSCI.0163-10.2010

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Motor Sequences and the Basal Ganglia: Kinematics, Not Habits
Michel Desmurget, Robert S. Turner
Journal of Neuroscience 2 June 2010, 30 (22) 7685-7690; DOI: 10.1523/JNEUROSCI.0163-10.2010
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