Article Information
- Received January 13, 2010
- Revision received April 26, 2010
- Accepted May 10, 2010
- First published June 30, 2010.
- Version of record published June 30, 2010.
Author Information
- Sandra Goebbels 1 ,*,
- Jan H. Oltrogge 1 ,*,
- Robert Kemper 1 ,*,
- Ingo Heilmann 2 ,
- Ingo Bormuth 1 , 3 ,
- Susanne Wolfer 1 ,
- Sven P. Wichert 1 ,
- Wiebke Möbius 1 ,
- Xin Liu 4 ,
- Corinna Lappe-Siefke 1 ,
- Moritz J. Rossner 1 ,
- Matthias Groszer 5 ,
- Ueli Suter 6 ,
- Jens Frahm 7 ,
- Susann Boretius 7 , and
- Klaus-Armin Nave 1
- 1Department of Neurogenetics, Max Planck Institute of Experimental Medicine, D-37075 Göttingen, Germany,
- 2Department of Plant Biochemistry, Georg August University Göttingen, D-37077 Göttingen, Germany,
- 3Charité, Universitätsmedizin Berlin, Institute of Cell Biology and Neurobiology, NeuroCure Cluster of Excellence, D-10117 Berlin, Germany,
- 4David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095,
- 5Inserm, Institut du Fer-à-Moulin, F-75005 Paris, France,
- 6Institute of Cell Biology, Department of Biology, Eidgenössische Technische Hochschule Zürich, CH-8093 Zürich, Switzerland, and
- 7Biomedizinische NMR Forschungs GmbH am Max-Planck-Institut für Biophysikalische Chemie, D-37070 Göttingen, Germany
- Correspondence should be addressed to either Dr. Sandra Goebbels or Dr. Klaus-Armin Nave, Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Hermann-Rein-Strasse 3, D-37075 Göttingen, Germany, sgoebbels{at}em.mpg.de or nave{at}em.mpg.de
Author contributions
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↵*S.G., J.H.O., and R.K. contributed equally to this work.
Disclosures
- Received January 13, 2010.
- Revision received April 26, 2010.
- Accepted May 10, 2010.
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This work was supported by Deutsche Forschungsgemeinschaft (Center for Molecular Physiology of the Brain) (K.-A.N., J.F.); the National Multiple Sclerosis Society, the Hertie Institute of Multiple Sclerosis Research, the Myelin Project, and Bundesministerium für Bildung und Forschung (Leukonet) (K.-A.N., M.J.R.); the European Community's Seventh Framework Programme (FP7/2007-1013) under Grant Agreement HEALTH-F2-2008-201535 (K.-A.N., S.G.); Deutsche Forschungsgemeinschaft Grant SFB 665 (I.B.); and the Swiss National Science Foundation and the National Center of Competence in Research “Neural Plasticity and Repair” (U.S.). We thank U. Bode for mouse genotyping, A. Fahrenholz for help with histology, G. Fricke-Bode for cell culture work, and T. Ruhwedel for help with electron microscopy. We gratefully acknowledge J. Archelos, C. Stiles, and M. Schachner for providing antibodies. We also thank P. Soriano for R26R-YFP indicator mice and members of the Nave Laboratory for helpful discussions.
- Correspondence should be addressed to either Dr. Sandra Goebbels or Dr. Klaus-Armin Nave, Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Hermann-Rein-Strasse 3, D-37075 Göttingen, Germany, sgoebbels{at}em.mpg.de or nave{at}em.mpg.de
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