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Articles, Behavioral/Systems/Cognitive

Developmental Differences in Medial Temporal Lobe Function during Memory Encoding

Simona Ghetti, Dana M. DeMaster, Andrew P. Yonelinas and Silvia A. Bunge
Journal of Neuroscience 14 July 2010, 30 (28) 9548-9556; https://doi.org/10.1523/JNEUROSCI.3500-09.2010
Simona Ghetti
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Dana M. DeMaster
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Andrew P. Yonelinas
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Silvia A. Bunge
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    Figure 1.

    Behavioral results. a, b, Hit and false-alarm rates (a) and rates of correct color recollection (b) as a function of age group. Error bars indicate SEs.

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    Figure 2.

    A, B, Average contrast values for each age group for ROIs in the left (L; A) and right (R; B) hippocampus, identified from the contrast Color Correct > Miss from all participants, p < 0.001. C, Contrast values for ROI in the right hippocampus from Color Correct > Color Incorrect from all participants, p < 0.001. Error bars indicate SEs. Significance levels are indicated as follows: **p < 0.01, *p < 0.05, •p < 0.10.

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    Figure 3.

    A, B, Average contrast values for each age group for ROIs in the left (L; A) and right (R; B) posterior parahippocampal gyrus, identified from the contrast Color Correct > Miss from all participants, p < 0.001. Error bars indicate SEs. Significance levels are indicated as follows: ***p < 0.001, **p < 01, *p < 0.05; ‡p = 0.05.

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    Figure 4.

    A, B, Average contrast values for each age group for ROIs in the right (R) DLPFC (A) and left (L) VLPFC (B) from the contrast Color Correct > Miss from all participants, p < 0.001. Error bars indicate SEs. Significance levels are indicated as follows: ***p < 0.001, **p < 01, *p < 0.05.

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    Table 1.

    Contrasts for clusters identified in the medial temporal lobes from Color Correct > Miss (all participants, p < 0.001 uncorrected) and Color Correct > Color Incorrect

    BAMNI coordinatesNo. voxelsPeak t value
    xyz
    Color Correct > Miss
        L Hippocampus−26−10−201664.32
        R Hippocampus30−12−201054.01
        L Posterior parahippocampal gyrus36−32−38−142045.98
        R Posterior parahippocampal gyrus3734−40−122485.72
    Color Correct > Color Incorrect
        L Hippocampus−12−360123.99
        L Hippocampus−24−10−20243.81
        L Parahippocampal gyrus35−22−24−20443.95
        L Posterior parahippocampal gyrus36−24−38−14103.73
        R Parahippocampal gyrus3532−26−22143.59
    • L, Left; R, right. All participants, p < 0.001, uncorrected.

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The Journal of Neuroscience: 30 (28)
Journal of Neuroscience
Vol. 30, Issue 28
14 Jul 2010
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Developmental Differences in Medial Temporal Lobe Function during Memory Encoding
Simona Ghetti, Dana M. DeMaster, Andrew P. Yonelinas, Silvia A. Bunge
Journal of Neuroscience 14 July 2010, 30 (28) 9548-9556; DOI: 10.1523/JNEUROSCI.3500-09.2010

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Developmental Differences in Medial Temporal Lobe Function during Memory Encoding
Simona Ghetti, Dana M. DeMaster, Andrew P. Yonelinas, Silvia A. Bunge
Journal of Neuroscience 14 July 2010, 30 (28) 9548-9556; DOI: 10.1523/JNEUROSCI.3500-09.2010
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