Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
    • Special Collections
  • EDITORIAL BOARD
    • Editorial Board
    • ECR Advisory Board
    • Journal Staff
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
    • Accessibility
  • SUBSCRIBE

User menu

  • Log out
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Neuroscience
  • Log out
  • Log in
  • My Cart
Journal of Neuroscience

Advanced Search

Submit a Manuscript
  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
    • Special Collections
  • EDITORIAL BOARD
    • Editorial Board
    • ECR Advisory Board
    • Journal Staff
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
    • Accessibility
  • SUBSCRIBE
PreviousNext
Articles, Behavioral/Systems/Cognitive

Incentive Learning Underlying Cocaine-Seeking Requires mGluR5 Receptors Located on Dopamine D1 Receptor-Expressing Neurons

Martin Novak, Briac Halbout, Eoin C. O'Connor, Jan Rodriguez Parkitna, Tian Su, Minqiang Chai, Hans S. Crombag, Ainhoa Bilbao, Rainer Spanagel, David N. Stephens, Günther Schütz and David Engblom
Journal of Neuroscience 8 September 2010, 30 (36) 11973-11982; https://doi.org/10.1523/JNEUROSCI.2550-10.2010
Martin Novak
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Briac Halbout
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Eoin C. O'Connor
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jan Rodriguez Parkitna
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tian Su
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Minqiang Chai
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hans S. Crombag
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ainhoa Bilbao
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rainer Spanagel
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David N. Stephens
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Günther Schütz
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David Engblom
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2550-10.2010
PubMed 
20826661
Published By 
Society for Neuroscience
History 
  • Received May 5, 2010
  • Revision received June 29, 2010
  • Accepted July 15, 2010
  • First published September 8, 2010.
  • Version of record published September 8, 2010.
Copyright & Usage 
Copyright © 2010 the authors 0270-6474/10/3011973-10$15.00/0

Author Information

  1. Martin Novak1,*,
  2. Briac Halbout2,*,
  3. Eoin C. O'Connor3,*,
  4. Jan Rodriguez Parkitna1,
  5. Tian Su1,
  6. Minqiang Chai1,
  7. Hans S. Crombag3,
  8. Ainhoa Bilbao2,
  9. Rainer Spanagel2,
  10. David N. Stephens3,
  11. Günther Schütz1, and
  12. David Engblom1,4
  1. 1Molecular Biology of the Cell I, German Cancer Research Center, 69120 Heidelberg, Germany,
  2. 2Department of Psychopharmacology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany,
  3. 3School of Psychology, University of Sussex, Brighton, BN1 9QG, United Kingdom, and
  4. 4Department of Clinical and Experimental Medicine, Linköping University, 58185, Linköping, Sweden
  1. Correspondence should be addressed to either of the following: David Engblom, Department of Clinical and Experimental Medicine, Linköping University, 58185, Linköping, Sweden, david.engblom{at}liu.se; David N. Stephens, School of Psychology, University of Sussex, Brighton BN1 9QG, UK, E-mail: d.stephens{at}sussex.ac.uk; or Rainer Spanagel, Department of Psychopharmacology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany, E-mail: rainer.spanagel{at}zi-mannheim.de
  • J. Rodriguez Parkitna's present address: Department of Molecular Neuropharmacology, Institute of Pharmacology of the Polish Academy of Sciences, 31-343 Cracow, Poland.

View Full Text

Author contributions

  • J. Rodriguez Parkitna's present address: Department of Molecular Neuropharmacology, Institute of Pharmacology of the Polish Academy of Sciences, 31-343 Cracow, Poland.

  1. ↵*M.N., B.H., and E.C.O. contributed equally to the work.

Disclosures

    • Received May 5, 2010.
    • Revision received June 29, 2010.
    • Accepted July 15, 2010.
  • This work was supported by the Deutsche Forschungsgemeinschaft through Collaborative Research Centers SFB 488 and SFB 636, by the Fonds der Chemischen Industrie, the European Union through Grant LSHM-CT-2005-018652 (CRESCENDO), the Bundesministerium für Bildung und Forschung through NGFNplus Grants FZK 01GS08153 and 01GS08142, the Helmholtz Gemeinschaft Deutscher Forschungszentren through Initiative CoReNe and Alliance HelMA, and the Deutsche Krebshilfe through project 108567. D.E. was supported by the Swedish Research Council, the Thuring, Wiberg and Jeansson foundations and the Swedish Society of Medicine. E.C.O. receives a studentship from the Biotechnology and Biological Sciences Research Council and Pfizer Inc. Research in D.N.S.'s laboratory is supported by the United Kingdom Medical Research Council. H.S.C. was supported by a Marie Curie reintegration award. We thank Ali Nasr Esfahani for help with immunohistochemistry, Milen Kirilov and Daniel Habermehl for input on short RNAs, and Witold Konopka for valuable suggestions.

  • Correspondence should be addressed to either of the following: David Engblom, Department of Clinical and Experimental Medicine, Linköping University, 58185, Linköping, Sweden, david.engblom{at}liu.se; David N. Stephens, School of Psychology, University of Sussex, Brighton BN1 9QG, UK, E-mail: d.stephens{at}sussex.ac.uk; or Rainer Spanagel, Department of Psychopharmacology, Central Institute of Mental Health, J5, 68159 Mannheim, Germany, E-mail: rainer.spanagel{at}zi-mannheim.de

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2025-06-19
to
E.g., 2025-06-19

Article usage: January 2018 to May 2025

AbstractFullPdf
Jan 201833110
Feb 201892211
Mar 20183686
Apr 20186724
May 20187376
Jun 20185247
Jul 20184256
Aug 20181164
Sep 20184436
Oct 20182287
Nov 20184263
Dec 20181252
Total 20184941772
Jan 20194204
Feb 201932813
Mar 20192264
Apr 201963216
May 201963516
Jun 201910297
Jul 20193166
Aug 20193277
Oct 20194366
Nov 201982811
Dec 20193239
Total 20195230099
Jan 202043410
Feb 2020717711
Mar 20201246
May 202011716
Jun 2020342
Jul 20202197
Aug 202043412
Sep 20208149
Oct 202052910
Nov 20206235
Dec 202032511
Total 20204440099
Jan 20215337
Feb 202152913
Mar 202163411
Apr 20216141
May 20217296
Jun 20211202
Jul 20213136
Aug 20210133
Sep 202172219
Oct 202161822
Nov 202141318
Dec 202151712
Total 202155255120
Jan 202211248
Feb 20229207
Mar 202213010
Apr 202212011
May 202211616
Jun 20221138
Jul 20223172
Aug 20228225
Sep 202211313
Oct 20229116
Nov 2022162
Dec 20220121
Total 20224620489
Jan 202342410
Feb 20232104
Mar 20236212
Apr 20232185
May 202372411
Jun 20235261
Jul 202323116
Aug 20234218
Sep 20231163
Oct 202392911
Nov 202333010
Dec 20236349
Total 20235128490
Jan 20247316
Feb 20241333
Mar 20245305
Apr 2024172285
May 20248202
Jun 20245152
Jul 202401811
Aug 20243128
Sep 202452913
Oct 202482938
Nov 202427115
Dec 20245346
Total 20246681484
Jan 20255207
Feb 202510449
Mar 20257347
Apr 202531914
May 20253144
Total 20252813141
Total3912805694
Back to top

In this issue

The Journal of Neuroscience: 30 (36)
Journal of Neuroscience
Vol. 30, Issue 36
8 Sep 2010
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Advertising (PDF)
  • Ed Board (PDF)
Email

Thank you for sharing this Journal of Neuroscience article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Incentive Learning Underlying Cocaine-Seeking Requires mGluR5 Receptors Located on Dopamine D1 Receptor-Expressing Neurons
(Your Name) has forwarded a page to you from Journal of Neuroscience
(Your Name) thought you would be interested in this article in Journal of Neuroscience.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Incentive Learning Underlying Cocaine-Seeking Requires mGluR5 Receptors Located on Dopamine D1 Receptor-Expressing Neurons
Martin Novak, Briac Halbout, Eoin C. O'Connor, Jan Rodriguez Parkitna, Tian Su, Minqiang Chai, Hans S. Crombag, Ainhoa Bilbao, Rainer Spanagel, David N. Stephens, Günther Schütz, David Engblom
Journal of Neuroscience 8 September 2010, 30 (36) 11973-11982; DOI: 10.1523/JNEUROSCI.2550-10.2010

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Request Permissions
Share
Incentive Learning Underlying Cocaine-Seeking Requires mGluR5 Receptors Located on Dopamine D1 Receptor-Expressing Neurons
Martin Novak, Briac Halbout, Eoin C. O'Connor, Jan Rodriguez Parkitna, Tian Su, Minqiang Chai, Hans S. Crombag, Ainhoa Bilbao, Rainer Spanagel, David N. Stephens, Günther Schütz, David Engblom
Journal of Neuroscience 8 September 2010, 30 (36) 11973-11982; DOI: 10.1523/JNEUROSCI.2550-10.2010
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Articles

  • Memory Retrieval Has a Dynamic Influence on the Maintenance Mechanisms That Are Sensitive to ζ-Inhibitory Peptide (ZIP)
  • Neurophysiological Evidence for a Cortical Contribution to the Wakefulness-Related Drive to Breathe Explaining Hypocapnia-Resistant Ventilation in Humans
  • Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase
Show more Articles

Behavioral/Systems/Cognitive

  • Influence of Reward on Corticospinal Excitability during Movement Preparation
  • Identification and Characterization of a Sleep-Active Cell Group in the Rostral Medullary Brainstem
  • Gravin Orchestrates Protein Kinase A and β2-Adrenergic Receptor Signaling Critical for Synaptic Plasticity and Memory
Show more Behavioral/Systems/Cognitive
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Issue Archive
  • Collections

Information

  • For Authors
  • For Advertisers
  • For the Media
  • For Subscribers

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Accessibility
(JNeurosci logo)
(SfN logo)

Copyright © 2025 by the Society for Neuroscience.
JNeurosci Online ISSN: 1529-2401

The ideas and opinions expressed in JNeurosci do not necessarily reflect those of SfN or the JNeurosci Editorial Board. Publication of an advertisement or other product mention in JNeurosci should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in JNeurosci.