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Articles, Neurobiology of Disease

Phosphorylation Dynamics Regulate Hsp27-Mediated Rescue of Neuronal Plasticity Deficits in Tau Transgenic Mice

Jose F. Abisambra, Laura J. Blair, Shannon E. Hill, Jeffrey R. Jones, Clara Kraft, Justin Rogers, John Koren III, Umesh K. Jinwal, Lisa Lawson, Amelia G. Johnson, Donna Wilcock, John C. O'Leary, Karen Jansen-West, Martin Muschol, Todd E. Golde, Edwin J. Weeber, Jessica Banko and Chad A. Dickey
Journal of Neuroscience 17 November 2010, 30 (46) 15374-15382; DOI: https://doi.org/10.1523/JNEUROSCI.3155-10.2010
Jose F. Abisambra
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Laura J. Blair
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Shannon E. Hill
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Jeffrey R. Jones
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Clara Kraft
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Justin Rogers
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John Koren III
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Umesh K. Jinwal
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Lisa Lawson
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Amelia G. Johnson
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Donna Wilcock
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John C. O'Leary
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Karen Jansen-West
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Martin Muschol
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Todd E. Golde
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Edwin J. Weeber
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Jessica Banko
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Chad A. Dickey
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.3155-10.2010
PubMed 
21084594
Published By 
Society for Neuroscience
History 
  • Received June 18, 2010
  • Revision received August 18, 2010
  • Accepted September 5, 2010
  • First published November 17, 2010.
  • Version of record published November 17, 2010.
Copyright & Usage 
Copyright © 2010 the authors 0270-6474/10/3015374-09$15.00/0

Author Information

  1. Jose F. Abisambra1,*,
  2. Laura J. Blair1,*,
  3. Shannon E. Hill3,
  4. Jeffrey R. Jones1,
  5. Clara Kraft1,
  6. Justin Rogers2,
  7. John Koren III1,
  8. Umesh K. Jinwal1,
  9. Lisa Lawson1,
  10. Amelia G. Johnson1,
  11. Donna Wilcock5,
  12. John C. O'Leary1,
  13. Karen Jansen-West4,
  14. Martin Muschol3,
  15. Todd E. Golde4,
  16. Edwin J. Weeber2,
  17. Jessica Banko2, and
  18. Chad A. Dickey1
  1. 1Departments of Molecular Medicine and
  2. 2Molecular Pharmacology and Physiology, University of South Florida Health Byrd Alzheimer's Institute, Tampa, Florida 33613, and
  3. 3Department of Physics, College of Arts and Sciences, University of South Florida, Tampa, Florida 33620,
  4. 4Department of Neuroscience, Mayo Clinic Jacksonville, Jacksonville, Florida 32224, and
  5. 5Department of Medicine/Division of Neurology, Duke University, Durham, North Carolina 27710
  1. Correspondence should be addressed to Dr. Chad Dickey, Department of Molecular Medicine, University of South Florida, 4001 East Fletcher Avenue, MDC 36, Tampa, FL 33613. cdickey{at}health.usf.edu
View Full Text

Author contributions

  1. ↵*J.F.A. and L.J.B. contributed equally to this work.

Disclosures

    • Received June 18, 2010.
    • Revision received August 18, 2010.
    • Accepted September 5, 2010.
  • C.A.D. was supported by National Institute on Aging Grant R00AG031291. J.F.A was supported by National Institutes on Aging Grant R00AG031291-02S1. We thank Dr. Peter Davies (Albert Einstein College of Medicine, New York, NY) for PHF1 tau antibody, Dr. Grant Mauk (University of British Columbia, Vancouver, BC, Canada) for contributing the 3×S/D Hsp27 clone, and the University of South Florida Health Lisa Muma Weitz microscopy core facility directed by Dr. Byeong Cha, which was used for these studies. We also acknowledge Dr. Michael Hutton and Dr. Leonard Petrucelli for insightful scientific discussions.

  • Correspondence should be addressed to Dr. Chad Dickey, Department of Molecular Medicine, University of South Florida, 4001 East Fletcher Avenue, MDC 36, Tampa, FL 33613. cdickey{at}health.usf.edu

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AbstractFullPdf
Nov 201024996202
Dec 20101017389
Total 2010350169291
Jan 2011464038
Feb 2011473128
Mar 2011803529
Apr 2011472313
May 2011303224
Jun 2011293017
Jul 2011492522
Aug 2011481918
Sep 2011361713
Oct 2011413329
Nov 2011592727
Dec 2011352619
Total 2011547338277
Jan 2012303123
Feb 2012572023
Mar 2012431317
Apr 2012511815
May 2012371813
Jun 2012221811
Jul 2012351418
Aug 2012302217
Sep 2012341310
Oct 2012281817
Nov 2012411114
Dec 2012341215
Total 2012442208193
Jan 2013361213
Feb 2013422615
Mar 201338128
Apr 2013351011
May 2013361716
Jun 2013471114
Jul 2013291914
Aug 2013351516
Sep 2013242211
Oct 201320810
Nov 201331815
Dec 201320108
Total 2013393170151
Jan 2014461213
Feb 201438149
Mar 201433129
Apr 201436154
May 2014311511
Jun 2014381617
Jul 2014452512
Aug 201437911
Sep 2014641611
Oct 201438167
Nov 20142377
Dec 2014201410
Total 2014449171121
Jan 201545109
Feb 2015351113
Mar 2015381511
Apr 201534811
May 2015301026
Jun 2015492048
Jul 20152953
Aug 2015251215
Sep 20152758
Oct 20153496
Nov 20152076
Dec 201525102
Total 2015391122158
Jan 20164538
Feb 20162256
Mar 20163167
Apr 20162188
May 201624716
Jun 201622105
Jul 201629138
Aug 20162975
Sep 201621102
Oct 2016172610
Nov 201610305
Dec 20164263
Total 201627515183
Jan 20173253
Feb 20171203
Mar 201711306
Apr 2017124010
May 20176354
Jun 20175175
Jul 201791412
Aug 20176114
Sep 20172156
Oct 20173206
Nov 20176236
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Total 20177227470
Jan 20187233
Feb 20189238
Mar 2018133612
Apr 20187285
May 20183402
Jun 20188426
Jul 201811183
Aug 20188242
Sep 20185254
Oct 20188308
Nov 20184223
Dec 20186231
Total 20188933457
Jan 20196338
Feb 20197164
Mar 201972411
Apr 201910157
May 201910208
Jun 20196216
Jul 201992711
Aug 20195143
Sep 20197147
Oct 20198217
Nov 2019101915
Dec 20199271
Total 20199425188
Jan 20208178
Feb 202010219
Mar 202071210
Apr 202011810
May 202022517
Jun 2020396
Jul 202061410
Aug 2020495
Sep 202053010
Oct 202034018
Nov 202073614
Dec 20207308
Total 202063261125
Jan 202113411
Feb 202154622
Mar 2021012
Total 202168135
Total317125301649
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The Journal of Neuroscience: 30 (46)
Journal of Neuroscience
Vol. 30, Issue 46
17 Nov 2010
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Phosphorylation Dynamics Regulate Hsp27-Mediated Rescue of Neuronal Plasticity Deficits in Tau Transgenic Mice
Jose F. Abisambra, Laura J. Blair, Shannon E. Hill, Jeffrey R. Jones, Clara Kraft, Justin Rogers, John Koren, Umesh K. Jinwal, Lisa Lawson, Amelia G. Johnson, Donna Wilcock, John C. O'Leary, Karen Jansen-West, Martin Muschol, Todd E. Golde, Edwin J. Weeber, Jessica Banko, Chad A. Dickey
Journal of Neuroscience 17 November 2010, 30 (46) 15374-15382; DOI: 10.1523/JNEUROSCI.3155-10.2010

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Phosphorylation Dynamics Regulate Hsp27-Mediated Rescue of Neuronal Plasticity Deficits in Tau Transgenic Mice
Jose F. Abisambra, Laura J. Blair, Shannon E. Hill, Jeffrey R. Jones, Clara Kraft, Justin Rogers, John Koren, Umesh K. Jinwal, Lisa Lawson, Amelia G. Johnson, Donna Wilcock, John C. O'Leary, Karen Jansen-West, Martin Muschol, Todd E. Golde, Edwin J. Weeber, Jessica Banko, Chad A. Dickey
Journal of Neuroscience 17 November 2010, 30 (46) 15374-15382; DOI: 10.1523/JNEUROSCI.3155-10.2010
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