Article Information
- Received June 29, 2010
- Revision received September 17, 2010
- Accepted October 14, 2010
- First published December 1, 2010.
- Version of record published December 1, 2010.
Author Information
- Jose M. Ibarz2,*,
- Guglielmo Foffani3,*,
- Elena Cid1,
- Marion Inostroza1, and
- Liset Menendez de la Prida1,*
- 1Instituto Cajal, Consejo Superior de Investigaciones Científicas, Madrid 28002, Spain,
- 2Neurobiología-Investigación, Hospital Ramón y Cajal, Madrid 28034, Spain, and
- 3Hospital Nacional de Parapléjicos, Servicio de Salud de Castilla la Mancha, Toledo 45071, Spain
- Correspondence should be addressed to Dr. Liset Menendez de la Prida, Instituto Cajal, Consejo Superior de Investigaciones Científicas, Avenida Doctor Arce, 37, Madrid 28002, Spain. lmprida{at}cajal.csic.es
Author contributions
↵*J.M.I., G.F., and L.M.P. contributed equally to this work.
Disclosures
- Received June 29, 2010.
- Revision received September 17, 2010.
- Accepted October 14, 2010.
This work was supported by grants from the Spanish Ministry Ministerio de Ciencia e Innovación (MICINN) (BFU2006-10584 and BFU2009-07989), the ERANET-Neuron project EPINet cofunded by the MICINN and the European Union Commission under FP7 (EUI2009-04093) and La Fundación para la Investigación Sanitaria en Castilla la Mancha (PI-2006/49). We thank Aric Agmon for useful comments and discussion and Richard Miles and Jozsef Csicsvari for critical comments on the manuscript. We also thank Albert Compte for inspiring discussions on the spectral entropy and Juan Aguilar for useful tips for juxtacellular recordings in vivo. L.M.P., G.F., and J.M.I. conceived the study. J.M.I. performed computational simulations; G.F. developed analytical tools and analyzed part of the data; E.C. was responsible for histological analysis and immunostaining; M.I. developed and handled the epileptic rats; and L.M.P. coordinated the study, performed the experiments, analyzed data, and wrote the paper.
- Correspondence should be addressed to Dr. Liset Menendez de la Prida, Instituto Cajal, Consejo Superior de Investigaciones Científicas, Avenida Doctor Arce, 37, Madrid 28002, Spain. lmprida{at}cajal.csic.es