This Week in The Journal

In cortical slices taken at the end of the dark period (when rats had been awake), AMPA receptor currents (blue) showed inward rectification: the EPSCs at positive holding potentials were smaller than those at negative holding potentials. Inward rectification was not detected in slices taken during the light period (red) when rats had been sleeping. See the article by Lanté et al. for details.