Correction: In “Diabetes-Associated SorCS1 Regulates Alzheimer's Amyloid-β Metabolism: Evidence for Involvement of SorL1 and the Retromer Complex,” by Rachel F. Lane, Summer M. Raines, John W. Steele, Michelle E. Ehrlich, James A. Lah, Scott A. Small, Rudolph E. Tanzi, Alan D. Attie, and Sam Gandy, which appeared on pages 13110–13115 of the September 29, 2010 issue, the article reports that Sorcs1 hypomorphs exhibit a 50% decrease in Sorcs1 mRNA transcripts relative to control levels (page 13113). Sorcs1 hypomorphs actually exhibit a more severe molecular phenotype. The correct value is a reduction in Sorcs1 mRNA transcript levels to 1/32 of control levels. The Sorcs1 hypomorph is therefore much closer to being a complete knock-out than initially reported, and this correction therefore strengthens the conclusions in the article.