Suppression of Alzheimer's Disease-Related Phenotypes by Expression of Heat Shock Protein 70 in Mice

Tatsuya Hoshino; Naoya Murao; Takushi Namba; Masaya Takehara; Hiroaki Adachi; Masahisa Katsuno; Gen Sobue; Takahide Matsushima; Toshiharu Suzuki; Tohru Mizushima

doi:10.1523/JNEUROSCI.5478-10.2011

Article Information

DOI

https://doi.org/10.1523/JNEUROSCI.5478-10.2011

PubMed

21471357

Published By

Society for Neuroscience

History

Received October 19, 2010
Revision received January 11, 2011
Accepted January 14, 2011
Published in print April 6, 2011.

Author Information

Tatsuya Hoshino¹,
Naoya Murao¹,
Takushi Namba¹,
Masaya Takehara¹,
Hiroaki Adachi²,
Masahisa Katsuno²,
Gen Sobue²,
Takahide Matsushima³,
Toshiharu Suzuki³, and
Tohru Mizushima¹

¹Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto 862-0973, Japan,
²Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan, and
³Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan

View Full Text

Author contributions

View Abstract

Disclosures

Received October 19, 2010.
Revision received January 11, 2011.
Accepted January 14, 2011.

This work was supported by Grants-in-Aid for Scientific Research from the Ministry of Health, Labour, and Welfare of Japan, as well as the Japan Science and Technology Agency, Grants-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan. We thank Drs. M. Staufenbiel (Novartis Institutes for BioMedical Research, Basel, Switzerland), and C. E. Angelidis and G. N. Pagoulatos (University of Ioannina, Ioannina, Greece) for providing transgenic mice.
Correspondence should be addressed to Tohru Mizushima, Graduate School of Medical and Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan. mizu{at}gpo.kumamoto-u.ac.jp

Statistics from Altmetric.com

Article usage

Select a custom date range for the past year

Article usage: April 2011 to December 2019

	Abstract	Full	Pdf
Apr 2011	2593	262	513
May 2011	622	89	119
Jun 2011	193	113	86
Jul 2011	107	56	55
Aug 2011	113	51	40
Sep 2011	89	48	40
Oct 2011	105	75	77
Nov 2011	91	94	123
Dec 2011	55	52	77
Total 2011	3968	840	1130
Jan 2012	75	96	82
Feb 2012	84	87	77
Mar 2012	56	52	55
Apr 2012	49	70	49
May 2012	56	55	42
Jun 2012	51	45	44
Jul 2012	41	39	37
Aug 2012	28	42	44
Sep 2012	26	44	29
Oct 2012	46	35	40
Nov 2012	60	43	39
Dec 2012	47	19	30
Total 2012	619	627	568
Jan 2013	54	67	32
Feb 2013	37	33	33
Mar 2013	45	38	39
Apr 2013	57	40	42
May 2013	35	22	30
Jun 2013	29	16	15
Jul 2013	51	31	37
Aug 2013	13	20	20
Sep 2013	21	16	35
Oct 2013	41	25	18
Nov 2013	28	59	26
Dec 2013	28	38	26
Total 2013	439	405	353
Jan 2014	35	76	66
Feb 2014	19	25	20
Mar 2014	38	31	33
Apr 2014	23	56	33
May 2014	23	48	35
Jun 2014	18	23	56
Jul 2014	44	38	37
Aug 2014	20	19	14
Sep 2014	30	42	25
Oct 2014	44	35	34
Nov 2014	28	26	22
Dec 2014	24	36	26
Total 2014	346	455	401
Jan 2015	28	39	24
Feb 2015	22	54	21
Mar 2015	27	44	23
Apr 2015	25	44	13
May 2015	13	7	9
Jun 2015	16	32	22
Jul 2015	17	26	21
Aug 2015	30	19	18
Sep 2015	15	23	17
Oct 2015	30	19	24
Nov 2015	24	15	10
Dec 2015	20	31	17
Total 2015	267	353	219
Jan 2016	33	19	7
Feb 2016	43	32	25
Mar 2016	32	24	22
Apr 2016	41	22	11
May 2016	15	12	11
Jun 2016	18	18	10
Jul 2016	16	17	8
Aug 2016	33	20	7
Sep 2016	30	21	16
Oct 2016	20	15	19
Nov 2016	7	40	31
Dec 2016	7	16	10
Total 2016	295	256	177
Jan 2017	9	30	6
Feb 2017	4	30	7
Mar 2017	9	24	12
Apr 2017	20	34	8
May 2017	3	19	6
Jun 2017	4	23	14
Jul 2017	6	18	6
Aug 2017	2	16	5
Sep 2017	1	22	8
Oct 2017	5	39	11
Nov 2017	16	40	10
Dec 2017	2	17	8
Total 2017	81	312	101
Jan 2018	2	39	10
Feb 2018	10	29	10
Mar 2018	6	27	4
Apr 2018	11	33	8
May 2018	3	81	13
Jun 2018	3	26	6
Jul 2018	2	38	9
Aug 2018	7	44	14
Sep 2018	8	31	7
Oct 2018	3	67	11
Nov 2018	2	72	11
Dec 2018	7	195	25
Total 2018	64	682	128
Jan 2019	4	334	22
Feb 2019	5	59	19
Mar 2019	9	45	19
Apr 2019	8	37	10
May 2019	4	27	7
Jun 2019	3	33	9
Jul 2019	6	32	16
Aug 2019	9	39	13
Sep 2019	5	20	9
Oct 2019	9	18	7
Nov 2019	4	18	17
Dec 2019	2	18	8
Total 2019	68	680	156
Total	6147	4610	3233