NMDA Receptors in Hippocampal GABAergic Synapses and Their Role in Nitric Oxide Signaling

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¹Laboratory of Cerebral Cortex Research, Institute of Experimental Medicine, Hungarian Academy of Sciences, H-1083, Budapest, Hungary,
²Division of Cerebral Structure, National Institute for Physiological Sciences, Okazaki 444-8787, Japan,
³Department of Anatomy, Hokkaido University School of Medicine, Sapporo 060-8638, Japan, and
⁴Laboratory for Behavioral Genetics, Brain Science Institute, RIKEN, Saitama 351-0198, Japan

Author contributions: E.S., T.F.F., and G.N. designed research; E.S., C.C., A.S., and G.N. performed research; Y.F., R.S., M.W., and S.I. contributed unpublished reagents/analytic tools; E.S. and G.N. analyzed data; E.S., T.F.F., and G.N. wrote the paper.

This work was supported by the Howard Hughes Medical Institute Grant 55005608; European Union Grants LSHM-CT-2004-005166 and LSHM-CT-2006-037315; Nemzeti Kutatási és Technológiai Hivatal–Országos Tudományos Kutatási Alapprogramok Grant CNK77793; and National Institutes of Health Grants DA09158, MH054671, and NS030549. G.N. was supported by János Bolyai Research Fellowship. E.S. and G.N. were supported by Japan Society for the Promotion of Science. We thank Prof. Jan de Vente for the cGMP antibody and Dr. N. Hájos and B. Németh for their help with slice preparations. We thank Drs. Takuji Iwasato and Reiko Ando for their help with the pyramidal cell-restricted GluN1 knock-out mice. The technical assistance of K. Lengyel, K. Iványi, and G. Goda is also acknowledged.
The authors declare no competing financial interests.
Correspondence should be addressed to Gábor Nyiri, Institute of Experimental Medicine, Hungarian Academy of Sciences, Szigony utca 43, H-1083, Budapest, Hungary. nyiri{at}koki.hu

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