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PubMed
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History
- Received August 3, 2010
- Revision received February 18, 2011
- Accepted February 24, 2011
- First published April 20, 2011.
- Version of record published April 20, 2011.
Copyright & Usage
Copyright © 2011 the authors 0270-6474/11/316221-14$15.00/0
Author Information
- Stephanie zur Nedden1,
- Simon Hawley2,
- Naomi Pentland2,3,
- D. Grahame Hardie2,
- Alexander S. Doney4, and
- Bruno G. Frenguelli1,3
- 1School of Life Sciences, University of Warwick, Coventry, CV4 7AL, United Kingdom,
- 2Division of Molecular Physiology, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, United Kingdom, and
- 3Departments of Pharmacology and Neuroscience and
- 4Medicine and Therapeutics, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, United Kingdom
Author contributions
Author contributions: D.G.H., A.S.D., and B.G.F. designed research; S.z.N., S.H., and N.P. performed research; S.z.N., S.H., and B.G.F. analyzed data; S.z.N., S.H., D.G.H., A.S.D., and B.G.F. wrote the paper.
Disclosures
- Received August 3, 2010.
- Revision received February 18, 2011.
- Accepted February 24, 2011.
We thank Jan Lopatar, Abigail Perkins, and Dr. Rajen Mistry for help with slice preparation and adenosine biosensor experiments and Prof. Nicholas Dale for valuable input, including the derivation of the slice thickness equation and use of HPLC equipment. We are grateful to Research into Ageing for funding a studentship to S.z.N. S.H. was supported by EXGENESIS Integrated Project Grant LSHM-CT-2004-005272 from the European Commission.
- Correspondence should be addressed to Prof. Bruno G. Frenguelli, School of Life Sciences, University of Warwick, Coventry CV4 7AL, UK. b.g.frenguelli{at}warwick.ac.uk
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