Cover legend: Reprogrammed neural crest stem cells derived from postnatal mouse dorsal root ganglion, expanded as neurospheres and differentiated into oligodendrocyte-like cells in vitro. Neurosphere cells differentiate into O4-positive cells (green) that coexpress Olig2 (red), a CNS-specific transcription factor of the oligodendroglial lineage, and display an oligodendrocyte-like morphology. Nuclei are stained with DAPI. For more information, see the article by Binder et al. in this issue (pages 6379–6391).