Article Information
- Received February 1, 2011
- Revision received March 30, 2011
- Accepted May 6, 2011
- First published July 6, 2011.
- Version of record published July 6, 2011.
Author Information
- Nicholas M. Kanaan1,2,3,
- Gerardo A. Morfini3,4,*,
- Nichole E. LaPointe3,5,
- Gustavo F. Pigino3,4,
- Kristina R. Patterson1,3,
- Yuyu Song3,4,
- Athena Andreadis6,
- Yifan Fu1,
- Scott T. Brady3,4,*, and
- Lester I. Binder1,*
- 1Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611,
- 2Division of Translational Science and Molecular Medicine, College of Human Medicine, Michigan State University, Grand Rapids, Michigan 49503,
- 3Marine Biological Laboratory, Woods Hole, Massachusetts 02543,
- 4Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, Illinois 60612,
- 5Neuroscience Research Institute, University of California, Santa Barbara, California 93106, and
- 6Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655
Author contributions
Author contributions: N.M.K., G.A.M., S.T.B., and L.I.B. designed research; N.M.K., G.A.M., N.E.L., G.F.P., K.R.P., Y.S., and S.T.B. performed research; N.M.K., G.A.M., A.A., Y.F., S.T.B., and L.I.B. contributed unpublished reagents/analytic tools; N.M.K., G.A.M., and Y.F. analyzed data; N.M.K., G.A.M., S.T.B., and L.I.B. wrote the paper.
↵*G.M., S.T.B., and L.I.B. contributed equally to this work.
Disclosures
- Received February 1, 2011.
- Revision received March 30, 2011.
- Accepted May 6, 2011.
This work was supported by NIH Grants T32 AG020506-07 (N.M.K.); AG09466 (L.I.B.); and NS23868, NS23320, and NS41170 (S.T.B.); as well as 2007/2008 MBL Summer Research Fellowships and an ALS/CVS Therapy Alliance grant (G.M.). We thank Alena Leitman, Sarah Berth, Agnieska Kaminska, Lisa Baker, Meryl Horn, Alex Sturbaum, and Yuka Atagi of the Brady and Morfini laboratories, who participated in our research at the Marine Biological Laboratory (Woods Hole, MA). We would also like to thank Juan Reyes for preparing some of the human tau samples and John Hardy (University College, London, UK) for drawing our attention to the Δ144-273 FTD mutation.
The authors declare no competing financial interests.
- Correspondence should be addressed to either of the following: Dr. Gerardo Morfini, University of Illinois at Chicago, Department of Anatomy and Cell Biology, 808 S. Wood Street, Room 578, Chicago, IL 60612, gmorfini{at}uic.edu; or Dr. Lester I. Binder, Northwestern University, Department of Cell and Molecular Biology, 303 E. Chicago Avenue, Tarry 8–754, Chicago, IL 60611, l-binder{at}northwestern.edu
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