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Articles, Cellular/Molecular

PIP2-Mediated HCN3 Channel Gating Is Crucial for Rhythmic Burst Firing in Thalamic Intergeniculate Leaflet Neurons

Shui-Wang Ying, Gareth R. Tibbs, Alessandra Picollo, Syed Y. Abbas, R. Lea Sanford, Alessio Accardi, Franz Hofmann, Andreas Ludwig and Peter A. Goldstein
Journal of Neuroscience 13 July 2011, 31 (28) 10412-10423; DOI: https://doi.org/10.1523/JNEUROSCI.0021-11.2011
Shui-Wang Ying
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Gareth R. Tibbs
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Alessandra Picollo
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Syed Y. Abbas
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R. Lea Sanford
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Alessio Accardi
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Franz Hofmann
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Andreas Ludwig
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Peter A. Goldstein
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0021-11.2011
PubMed 
21753018
Published By 
Society for Neuroscience
History 
  • Received December 23, 2010
  • Revision received April 21, 2011
  • Accepted May 30, 2011
  • First published July 13, 2011.
  • Version of record published July 13, 2011.
Copyright & Usage 
Copyright © 2011 the authors 0270-6474/11/3110412-12$15.00/0

Author Information

  1. Shui-Wang Ying1,
  2. Gareth R. Tibbs,
  3. Alessandra Picollo1,
  4. Syed Y. Abbas1,
  5. R. Lea Sanford1,
  6. Alessio Accardi1,2,
  7. Franz Hofmann3,
  8. Andreas Ludwig4, and
  9. Peter A. Goldstein1
  1. 1Departments of Anesthesiology and
  2. 2Physiology and Biophysics and Biochemistry, Weill Cornell Medical College, New York, New York 10065,
  3. 3Institut für Pharmakologie und Toxikologie, Technische Universität München, 80802 München, Germany, and
  4. 4Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany
  • S. Y. Abbas's present address: Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461.

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Author contributions

  1. Author contributions: S.-W.Y., G.R.T., A.P., S.Y.A., R.L.S., A.A., and P.A.G. designed research; S.-W.Y., G.R.T., A.P., S.Y.A., and R.L.S. performed research; F.H. and A.L. contributed unpublished reagents/analytic tools; S.-W.Y., G.R.T., A.P., S.Y.A., and P.A.G. analyzed data; S.-W.Y., G.R.T., and P.A.G. wrote the paper.

  • S. Y. Abbas's present address: Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461.

Disclosures

    • Received December 23, 2010.
    • Revision received April 21, 2011.
    • Accepted May 30, 2011.
  • This work was supported by the Department of Anesthesiology, Weill Cornell Medical College. We thank Juliane Stieber, University Erlangen-Nürnberg, for generously providing the HCN3 clone and John Riley and members of Steven Siegelbaum's laboratory for generously providing us with oocytes.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dr. Shui-Wang Ying, C.V. Starr Lab for Molecular Neuropharmacology, Department of Anesthesiology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10065. svy2001{at}med.cornell.edu

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Oct 202112532
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Mar 20222172
Apr 20220167
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Jul 20221144
Aug 20222116
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Total 20221917773
Jan 20231245
Feb 20230118
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Apr 202341611
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Jun 20230207
Jul 202311512
Aug 20230168
Sep 20231189
Total 2023815276
Total1471350523
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The Journal of Neuroscience: 31 (28)
Journal of Neuroscience
Vol. 31, Issue 28
13 Jul 2011
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PIP2-Mediated HCN3 Channel Gating Is Crucial for Rhythmic Burst Firing in Thalamic Intergeniculate Leaflet Neurons
Shui-Wang Ying, Gareth R. Tibbs, Alessandra Picollo, Syed Y. Abbas, R. Lea Sanford, Alessio Accardi, Franz Hofmann, Andreas Ludwig, Peter A. Goldstein
Journal of Neuroscience 13 July 2011, 31 (28) 10412-10423; DOI: 10.1523/JNEUROSCI.0021-11.2011

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PIP2-Mediated HCN3 Channel Gating Is Crucial for Rhythmic Burst Firing in Thalamic Intergeniculate Leaflet Neurons
Shui-Wang Ying, Gareth R. Tibbs, Alessandra Picollo, Syed Y. Abbas, R. Lea Sanford, Alessio Accardi, Franz Hofmann, Andreas Ludwig, Peter A. Goldstein
Journal of Neuroscience 13 July 2011, 31 (28) 10412-10423; DOI: 10.1523/JNEUROSCI.0021-11.2011
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