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Articles, Behavioral/Systems/Cognitive

Inflammation-Induced Lethargy Is Mediated by Suppression of Orexin Neuron Activity

Aaron J. Grossberg, XinXia Zhu, Gina M. Leinninger, Peter R. Levasseur, Theodore P. Braun, Martin G. Myers Jr and Daniel L. Marks
Journal of Neuroscience 3 August 2011, 31 (31) 11376-11386; DOI: https://doi.org/10.1523/JNEUROSCI.2311-11.2011
Aaron J. Grossberg
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XinXia Zhu
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Gina M. Leinninger
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Peter R. Levasseur
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Theodore P. Braun
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Martin G. Myers Jr
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Daniel L. Marks
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2311-11.2011
PubMed 
21813697
Published By 
Society for Neuroscience
History 
  • Received May 6, 2011
  • Revision received June 13, 2011
  • Accepted June 28, 2011
  • First published August 3, 2011.
  • Version of record published August 3, 2011.
Copyright & Usage 
Copyright © 2011 the authors 0270-6474/11/3111376-11$15.00/0

Author Information

  1. Aaron J. Grossberg1,2,
  2. XinXia Zhu2,
  3. Gina M. Leinninger3,
  4. Peter R. Levasseur2,
  5. Theodore P. Braun2,
  6. Martin G. Myers Jr3,4, and
  7. Daniel L. Marks2
  1. 1Neuroscience Graduate Program, and
  2. 2Papé Family Pediatric Research Institute, Department of Pediatrics, Oregon Health & Science University, Portland, Oregon 97239, and
  3. 3Division of Metabolism, Endocrinology, and Diabetes, Department of Internal Medicine, and
  4. 4Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan 48109
View Full Text

Author contributions

  1. Author contributions: A.J.G., T.P.B., and D.L.M. designed research; A.J.G., X.Z., G.M.L., and P.R.L. performed research; G.M.L. and M.G.M. contributed unpublished reagents/analytic tools; A.J.G. and D.L.M. analyzed data; A.J.G. and D.L.M. wrote the paper.

View Abstract

Disclosures

    • Received May 6, 2011.
    • Revision received June 13, 2011.
    • Accepted June 28, 2011.
  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dr. Daniel L. Marks, Papé Family Pediatric Research Institute, Department of Pediatrics, Oregon Health & Science University, Mail Code L-481, 3181 SW Sam Jackson Park Road, Portland, OR 97239. marksd{at}ohsu.edu

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Aug 20112284116270
Sep 20112103230
Oct 20111264445
Nov 20111075132
Dec 2011564228
Total 20112783285405
Jan 2012713027
Feb 2012424233
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Apr 2012283425
May 2012453725
Jun 2012362527
Jul 2012253321
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Total 2012480373321
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Jul 2013172716
Aug 2013152414
Sep 2013121817
Oct 2013274131
Nov 2013141717
Dec 2013232314
Total 2013273300223
Jan 2014221913
Feb 201415199
Mar 2014212514
Apr 20142530822
May 2014246523
Jun 2014185814
Jul 201418439
Aug 2014284115
Sep 2014213914
Oct 2014232914
Nov 2014133813
Dec 2014143016
Total 2014242714176
Jan 201524768
Feb 2015124018
Mar 2015335617
Apr 2015154113
May 2015264926
Jun 2015101310
Jul 2015243113
Aug 201516347
Sep 201516419
Oct 201513284
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Dec 201518339
Total 2015238493147
Jan 2016222814
Feb 2016203011
Mar 201634219
Apr 201624167
May 201613126
Jun 2016152418
Jul 201628278
Aug 2016282412
Sep 201622158
Oct 201617167
Nov 201613189
Dec 20164223
Total 2016240253112
Jan 20176278
Feb 20176447
Mar 2017125315
Apr 2017115649
May 20179358
Jun 20172375
Jul 20171245
Aug 20177256
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Total 201776426135
Jan 201812424
Feb 20188566
Mar 201813407
Apr 2018114313
May 20187296
Jun 20188504
Jul 20184382
Aug 20186818
Sep 20182594
Oct 20184636
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Total 20188459974
Jan 201984218
Feb 20197447
Mar 2019113914
Apr 20199479
May 2019124614
Jun 2019233110
Jul 201913429
Aug 20194639
Sep 20197337
Oct 20198393
Nov 2019175914
Dec 201956116
Total 2019124546130
Jan 20203608
Feb 20205639
Mar 20208987
Apr 202066114
May 202014574
Jun 2020105711
Jul 20203528
Aug 20200502
Sep 202096512
Oct 202087012
Nov 2020147811
Dec 2020161037
Total 202096814105
Jan 202178819
Total 202178819
Total464348911847
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The Journal of Neuroscience: 31 (31)
Journal of Neuroscience
Vol. 31, Issue 31
3 Aug 2011
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Inflammation-Induced Lethargy Is Mediated by Suppression of Orexin Neuron Activity
Aaron J. Grossberg, XinXia Zhu, Gina M. Leinninger, Peter R. Levasseur, Theodore P. Braun, Martin G. Myers, Daniel L. Marks
Journal of Neuroscience 3 August 2011, 31 (31) 11376-11386; DOI: 10.1523/JNEUROSCI.2311-11.2011

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Inflammation-Induced Lethargy Is Mediated by Suppression of Orexin Neuron Activity
Aaron J. Grossberg, XinXia Zhu, Gina M. Leinninger, Peter R. Levasseur, Theodore P. Braun, Martin G. Myers, Daniel L. Marks
Journal of Neuroscience 3 August 2011, 31 (31) 11376-11386; DOI: 10.1523/JNEUROSCI.2311-11.2011
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