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Articles, Cellular/Molecular

Acute Cocaine Exposure Weakens GABAB Receptor-Dependent G-Protein-Gated Inwardly Rectifying K+ Signaling in Dopamine Neurons of the Ventral Tegmental Area

Devinder Arora, Matthew Hearing, Desirae M. Haluk, Kelsey Mirkovic, Ana Fajardo-Serrano, Martin W. Wessendorf, Masahiko Watanabe, Rafael Luján and Kevin Wickman
Journal of Neuroscience 24 August 2011, 31 (34) 12251-12257; https://doi.org/10.1523/JNEUROSCI.0494-11.2011
Devinder Arora
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Matthew Hearing
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Desirae M. Haluk
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Kelsey Mirkovic
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Ana Fajardo-Serrano
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Martin W. Wessendorf
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Masahiko Watanabe
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Rafael Luján
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Kevin Wickman
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0494-11.2011
PubMed 
21865468
Published By 
Society for Neuroscience
History 
  • Received January 28, 2011
  • Revision received June 24, 2011
  • Accepted June 29, 2011
  • First published August 24, 2011.
  • Version of record published August 24, 2011.
Copyright & Usage 
Copyright © 2011 the authors 0270-6474/11/3112251-07$15.00/0

Author Information

  1. Devinder Arora1,*,
  2. Matthew Hearing1,*,
  3. Desirae M. Haluk1,*,
  4. Kelsey Mirkovic1,
  5. Ana Fajardo-Serrano3,
  6. Martin W. Wessendorf2,
  7. Masahiko Watanabe4,
  8. Rafael Luján3, and
  9. Kevin Wickman1
  1. 1Departments of Pharmacology and
  2. 2Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455,
  3. 3Departamento de Ciencias Médicas, Universidad de Castilla–La Mancha, 02006 Albacete, Spain, and
  4. 4Department of Anatomy, Hokkaido University School of Medicine, Sapporo 060-8638, Japan
View Full Text

Author contributions

  1. Author contributions: D.A., M.H., D.M.H., K.M., A.F.-S., M.W.W., R.L., and K.W. designed research; D.A., M.H., D.M.H., K.M., A.F.-S., M.W.W., and R.L. performed research; M.W. contributed unpublished reagents/analytic tools; D.A., M.H., D.M.H., K.M., A.F.-S., M.W.W., R.L., and K.W. analyzed data; M.H. and K.W. wrote the paper.

  2. ↵*D.A., M.H., and D.M.H. contributed equally to this work.

Disclosures

    • Received January 28, 2011.
    • Revision received June 24, 2011.
    • Accepted June 29, 2011.
  • This work was supported by NIH Grants R01 MH061933 (K.W.), P50 DA011806 (K.W.), R21 DA029343 (K.W.), T32 DA007234 (K.M.), T32 DA007097 (M.H.), and R01 DA017758 (M.W.W.), and Spanish Ministry of Science and Innovation Grants BFU2009-08404/BFI and CONSOLIDER-Ingenio CSD2008-00005 (R.L.). We thank Daniele Young for assistance with the mouse colony. We also thank Rebecca Speltz-Paiz and Ruichi Shigemoto for their technical assistance.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Kevin Wickman, Department of Pharmacology, University of Minnesota, 6-120 Jackson Hall, 321 Church Street Southeast, Minneapolis, MN 55455. wickm002{at}umn.edu

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Jan 20183154
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Mar 20183226
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Feb 201916266
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Apr 202131815
May 20214167
Jun 20212204
Jul 20210115
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Sep 20212238
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Total 202140203130
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Jun 202522513
Jul 202502012
Aug 202522021
Sep 202582919
Oct 20255418
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Dec 20252164
Total 202533412145
Total3352172767
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The Journal of Neuroscience: 31 (34)
Journal of Neuroscience
Vol. 31, Issue 34
24 Aug 2011
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Acute Cocaine Exposure Weakens GABAB Receptor-Dependent G-Protein-Gated Inwardly Rectifying K+ Signaling in Dopamine Neurons of the Ventral Tegmental Area
Devinder Arora, Matthew Hearing, Desirae M. Haluk, Kelsey Mirkovic, Ana Fajardo-Serrano, Martin W. Wessendorf, Masahiko Watanabe, Rafael Luján, Kevin Wickman
Journal of Neuroscience 24 August 2011, 31 (34) 12251-12257; DOI: 10.1523/JNEUROSCI.0494-11.2011

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Acute Cocaine Exposure Weakens GABAB Receptor-Dependent G-Protein-Gated Inwardly Rectifying K+ Signaling in Dopamine Neurons of the Ventral Tegmental Area
Devinder Arora, Matthew Hearing, Desirae M. Haluk, Kelsey Mirkovic, Ana Fajardo-Serrano, Martin W. Wessendorf, Masahiko Watanabe, Rafael Luján, Kevin Wickman
Journal of Neuroscience 24 August 2011, 31 (34) 12251-12257; DOI: 10.1523/JNEUROSCI.0494-11.2011
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