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Articles, Cellular/Molecular

Two Amino Acid Residues Contribute to a Cation-π Binding Interaction in the Binding Site of an Insect GABA Receptor

Sarah C. R. Lummis, Ian McGonigle, Jamie A. Ashby and Dennis A. Dougherty
Journal of Neuroscience 24 August 2011, 31 (34) 12371-12376; DOI: https://doi.org/10.1523/JNEUROSCI.1610-11.2011
Sarah C. R. Lummis
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Ian McGonigle
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Jamie A. Ashby
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Dennis A. Dougherty
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1610-11.2011
PubMed 
21865479
Published By 
Society for Neuroscience
History 
  • Received March 31, 2011
  • Revision received June 8, 2011
  • Accepted June 24, 2011
  • First published August 24, 2011.
  • Version of record published August 24, 2011.
Copyright & Usage 
Copyright © 2011 the authors 0270-6474/11/3112371-06$15.00/0

Author Information

  1. Sarah C. R. Lummis1,
  2. Ian McGonigle1,
  3. Jamie A. Ashby1, and
  4. Dennis A. Dougherty2
  1. 1Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, United Kingdom, and
  2. 2Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125
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Author contributions

  1. Author contributions: S.C.R.L. designed research; S.C.R.L., I.M., and J.A.A. performed research; D.A.D. contributed unpublished reagents/analytic tools; S.C.R.L., I.M., and J.A.A. analyzed data; S.C.R.L. and D.A.D. wrote the paper.

Disclosures

    • Received March 31, 2011.
    • Revision received June 8, 2011.
    • Accepted June 24, 2011.
  • We thank The Wellcome Trust (WT 81925; S.C.R.L. is a Wellcome Trust Senior Research Fellow in Basic Biomedical Science), the Medical Research Council (a studentship to I.M.), the European Union (FP7 NeuroCypres; J.A.A., S.C.R.L.), and the U.S. National Institutes of Health (NS34407, D.A.D.).

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Sarah C. R. Lummis, Department of Biochemistry, University of Cambridge, Downing Site, Cambridge CB2 1QW, UK. sl120{at}cam.ac.uk

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Jan 20181143
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Apr 20184214
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Sep 20180351
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Feb 20196254
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May 20191145
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May 20201199
Jun 20202113
Jul 2020386
Aug 20206905
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Jan 20214167
Feb 20217144
Mar 202132314
Apr 202121110
May 20218206
Jun 20213117
Jul 2021088
Aug 20212106
Sep 20213154
Oct 202122821
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Dec 20210123
Total 202142187105
Jan 20221154
Feb 20222141
Mar 20220165
Apr 20224163
May 202231211
Jun 202201711
Jul 20223103
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Total 20221310639
Total1221037300
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The Journal of Neuroscience: 31 (34)
Journal of Neuroscience
Vol. 31, Issue 34
24 Aug 2011
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Two Amino Acid Residues Contribute to a Cation-π Binding Interaction in the Binding Site of an Insect GABA Receptor
Sarah C. R. Lummis, Ian McGonigle, Jamie A. Ashby, Dennis A. Dougherty
Journal of Neuroscience 24 August 2011, 31 (34) 12371-12376; DOI: 10.1523/JNEUROSCI.1610-11.2011

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Two Amino Acid Residues Contribute to a Cation-π Binding Interaction in the Binding Site of an Insect GABA Receptor
Sarah C. R. Lummis, Ian McGonigle, Jamie A. Ashby, Dennis A. Dougherty
Journal of Neuroscience 24 August 2011, 31 (34) 12371-12376; DOI: 10.1523/JNEUROSCI.1610-11.2011
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