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Articles, Cellular/Molecular

The Residence Time of GABAARs at Inhibitory Synapses Is Determined by Direct Binding of the Receptor α1 Subunit to Gephyrin

Jayanta Mukherjee, Karla Kretschmannova, Geraldine Gouzer, Hans-Michael Maric, Sarah Ramsden, Verena Tretter, Kirsten Harvey, Paul A. Davies, Antoine Triller, Hermann Schindelin and Stephen J. Moss
Journal of Neuroscience 12 October 2011, 31 (41) 14677-14687; DOI: https://doi.org/10.1523/JNEUROSCI.2001-11.2011
Jayanta Mukherjee
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Karla Kretschmannova
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Geraldine Gouzer
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Hans-Michael Maric
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Sarah Ramsden
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Verena Tretter
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Kirsten Harvey
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Paul A. Davies
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Antoine Triller
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Hermann Schindelin
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Stephen J. Moss
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2001-11.2011
PubMed 
21994384
Published By 
Society for Neuroscience
History 
  • Received April 12, 2011
  • Revision received August 16, 2011
  • Accepted August 20, 2011
  • First published October 12, 2011.
  • Version of record published October 12, 2011.
Copyright & Usage 
Copyright © 2011 the authors 0270-6474/11/3114677-11$15.00/0

Author Information

  1. Jayanta Mukherjee1,
  2. Karla Kretschmannova1,*,
  3. Geraldine Gouzer2,*,
  4. Hans-Michael Maric3,*,
  5. Sarah Ramsden4,
  6. Verena Tretter5,
  7. Kirsten Harvey4,
  8. Paul A. Davies1,
  9. Antoine Triller2,
  10. Hermann Schindelin3, and
  11. Stephen J. Moss1,6
  1. 1Department of Neuroscience, Tufts University School of Medicine, Boston, Massachusetts 02111,
  2. 2Ecole Normale Supérieure, Inserm U1024, 75230 Paris Cedex 05, France,
  3. 3Rudolf Virchow Center for Experimental Biomedicine, Institute of Structural Biology, University of Würzburg, 97080 Würzburg, Germany,
  4. 4Department of Pharmacology, The School of Pharmacy, London WC1N 1AX, United Kingdom,
  5. 5Department of Biochemistry and Molecular Biology, Medical University Vienna Center for Brain Research, 1090 Vienna, Austria, and
  6. 6Department of Neuroscience, Physiology and Pharmacology, University College, London WC1 6BT, United Kingdom
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Author contributions

  1. Author contributions: J.M., K.K., K.H., A.T., H.S., and S.J.M. designed research; J.M., K.K., G.G., H.-M.M., and S.R. performed research; J.M., K.K., G.G., H.-M.M., V.T., K.H., P.A.D., A.T., H.S., and S.J.M. analyzed data; J.M., K.K., G.G., A.T., H.S., and S.J.M. wrote the paper.

  2. ↵*K.K., G.G., and H.-M.M. contributed equally to this work.

Disclosures

    • Received April 12, 2011.
    • Revision received August 16, 2011.
    • Accepted August 20, 2011.
  • This work was supported by National Institute of Neurological Disorders and Stroke Grants NS047478, NS48045, NS051195, NS054900, NS056359, and NS065725 and a Sponsored Research Agreement from AstraZeneca. The work of H.S. was supported by Deutsche Forschungsgemeinschaft Grants FZ 82 and SFB 487C7. A.T. was supported by Fondation de la Recherche Médicale and Agence National de la Recherche Grant ANR-R08072JJ.

  • Correspondence should be addressed to Stephen J. Moss at the above address. stephen.moss{at}tufts.edu

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The Journal of Neuroscience: 31 (41)
Journal of Neuroscience
Vol. 31, Issue 41
12 Oct 2011
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The Residence Time of GABAARs at Inhibitory Synapses Is Determined by Direct Binding of the Receptor α1 Subunit to Gephyrin
Jayanta Mukherjee, Karla Kretschmannova, Geraldine Gouzer, Hans-Michael Maric, Sarah Ramsden, Verena Tretter, Kirsten Harvey, Paul A. Davies, Antoine Triller, Hermann Schindelin, Stephen J. Moss
Journal of Neuroscience 12 October 2011, 31 (41) 14677-14687; DOI: 10.1523/JNEUROSCI.2001-11.2011

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The Residence Time of GABAARs at Inhibitory Synapses Is Determined by Direct Binding of the Receptor α1 Subunit to Gephyrin
Jayanta Mukherjee, Karla Kretschmannova, Geraldine Gouzer, Hans-Michael Maric, Sarah Ramsden, Verena Tretter, Kirsten Harvey, Paul A. Davies, Antoine Triller, Hermann Schindelin, Stephen J. Moss
Journal of Neuroscience 12 October 2011, 31 (41) 14677-14687; DOI: 10.1523/JNEUROSCI.2001-11.2011
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