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Articles, Neurobiology of Disease

Sensory Network Dysfunction, Behavioral Impairments, and Their Reversibility in an Alzheimer's β-Amyloidosis Mouse Model

Daniel W. Wesson, Anne H. Borkowski, Gary E. Landreth, Ralph A. Nixon, Efrat Levy and Donald A. Wilson
Journal of Neuroscience 2 November 2011, 31 (44) 15962-15971; DOI: https://doi.org/10.1523/JNEUROSCI.2085-11.2011
Daniel W. Wesson
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Anne H. Borkowski
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Gary E. Landreth
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Ralph A. Nixon
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Efrat Levy
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Donald A. Wilson
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2085-11.2011
PubMed 
22049439
Published By 
Society for Neuroscience
History 
  • Received April 22, 2011
  • Revision received August 4, 2011
  • Accepted August 24, 2011
  • First published November 2, 2011.
  • Version of record published November 2, 2011.
Copyright & Usage 
Copyright © 2011 the authors 0270-6474/11/3115962-10$15.00/0

Author Information

  1. Daniel W. Wesson1,3,7,8,
  2. Anne H. Borkowski1,
  3. Gary E. Landreth8,
  4. Ralph A. Nixon2,4,5,7,
  5. Efrat Levy2,4,6,7, and
  6. Donald A. Wilson1,3,7,9
  1. 1Emotional Brain Institute and
  2. 2Center for Dementia Research, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York, 10962,
  3. 3Departments of Child and Adolescent Psychiatry,
  4. 4Psychiatry,
  5. 5Cell Biology, and
  6. 6Pharmacology and
  7. 7Center of Excellence on Brain Aging, New York University School of Medicine, New York, New York, 10016,
  8. 8Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, 44106, and
  9. 9Center for Neural Studies, New York University, New York, New York, 10003
View Full Text

Author contributions

  1. Author contributions: D.W.W. and D.A.W. designed research; D.W.W. and A.H.B. performed research; D.W.W. and A.H.B. analyzed data; D.W.W., A.H.B., G.E.L., R.A.N., E.L., and D.A.W. wrote the paper.

Disclosures

    • Received April 22, 2011.
    • Revision received August 4, 2011.
    • Accepted August 24, 2011.
  • This work was supported by National Institutes of Health Grants DC003906 (D.A.W.), AG037693 (D.A.W, E.L., R.A.N.), AG017617 (R.A.N.), and AG030482 (G.E.L.). We thank Julie Chapuis for helpful comments on a previous version of this manuscript, Paige Cramer and Paul Mathews for advice on ELISAs, and Adrienn Varga-Wesson for assistance performing ELISAs.

  • Correspondence to be addressed to Daniel Wesson, Case Western Reserve University, Department of Neurosciences, 10900 Euclid Avenue, Cleveland, OH 44106. dww53{at}case.edu

Online Impact

 

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AbstractFullPdf
Jan 201853611
Feb 201832618
Mar 20184399
Apr 20184339
May 20186464
Jun 20181303
Jul 201842615
Aug 20181254
Sep 201822623
Oct 201833377
Nov 201847810
Dec 20185316
Total 20184296999
Jan 201911316
Feb 2019383312
Mar 2019362412
Apr 2019232114
May 201928158
Jun 201928308
Jul 2019331610
Aug 201923129
Oct 201932259
Nov 2019311910
Dec 201932218
Total 2019315247106
Jan 202028258
Feb 2020522824
Mar 2020461411
May 2020402011
Jun 2020453615
Jul 2020561110
Aug 202029107
Sep 202011169
Oct 2020102314
Nov 202072915
Dec 20208299
Total 2020332241133
Jan 202162410
Feb 202193513
Mar 202114338
Apr 2021182225
May 2021221913
Jun 202134269
Jul 2021341417
Aug 2021461717
Sep 2021351412
Oct 2021453032
Nov 2021411019
Dec 202138187
Total 2021342262182
Jan 2022381917
Feb 2022501914
Mar 2022521814
Apr 2022412515
May 2022461621
Jun 2022411610
Jul 2022491613
Aug 2022421918
Sep 2022471918
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Dec 2022262414
Total 2022494218182
Jan 2023544719
Feb 2023382212
Mar 2023422410
Apr 2023492510
May 2023322713
Total 202321514564
Total17402082766
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The Journal of Neuroscience: 31 (44)
Journal of Neuroscience
Vol. 31, Issue 44
2 Nov 2011
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Sensory Network Dysfunction, Behavioral Impairments, and Their Reversibility in an Alzheimer's β-Amyloidosis Mouse Model
Daniel W. Wesson, Anne H. Borkowski, Gary E. Landreth, Ralph A. Nixon, Efrat Levy, Donald A. Wilson
Journal of Neuroscience 2 November 2011, 31 (44) 15962-15971; DOI: 10.1523/JNEUROSCI.2085-11.2011

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Sensory Network Dysfunction, Behavioral Impairments, and Their Reversibility in an Alzheimer's β-Amyloidosis Mouse Model
Daniel W. Wesson, Anne H. Borkowski, Gary E. Landreth, Ralph A. Nixon, Efrat Levy, Donald A. Wilson
Journal of Neuroscience 2 November 2011, 31 (44) 15962-15971; DOI: 10.1523/JNEUROSCI.2085-11.2011
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