Robust Central Reduction of Amyloid-β in Humans with an Orally Available, Non-Peptidic β-Secretase Inhibitor
Patrick C. May, Robert A. Dean, Stephen L. Lowe, Ferenc Martenyi, Scott M. Sheehan, Leonard N. Boggs, Scott A. Monk, Brian M. Mathes, Dustin J. Mergott, Brian M. Watson, Stephanie L. Stout, David E. Timm, Elizabeth Smith LaBell, Celedon R. Gonzales, Masako Nakano, Stanford S. Jhee, Mark Yen, Larry Ereshefsky, Terry D. Lindstrom, David O. Calligaro, Patrick J. Cocke, D. Greg Hall, Stuart Friedrich, Martin Citron and James E. Audia
Journal of Neuroscience 16 November 2011, 31 (46) 16507-16516; https://doi.org/10.1523/JNEUROSCI.3647-11.2011