Article Information
- Received May 22, 2010
- Revision received October 27, 2010
- Accepted November 16, 2010
- First published February 2, 2011.
- Version of record published February 2, 2011.
Author Information
- Olivia A. Shipton1,*,
- Julie R. Leitz1,*,
- Jenny Dworzak1,
- Christine E. J. Acton1,
- Elizabeth M. Tunbridge2,
- Franziska Denk1,
- Hana N. Dawson3,
- Michael P. Vitek3,
- Richard Wade-Martins1,4,
- Ole Paulsen1,5, and
- Mariana Vargas-Caballero1
- 1Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom,
- 2Department of Psychiatry, Warneford Hospital, Oxford, OX3 7JX, United Kingdom,
- 3Division of Neurology, Duke University, Durham, North Carolina 27710,
- 4Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford OX1 3QX, United Kingdom, and
- 5Physiological Laboratory, Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge CB2 3EG, United Kingdom
- Correspondence should be addressed to either of the following: Dr. Mariana Vargas-Caballero, Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom, mariana.vargas{at}dpag.ox.ac.uk; or Prof. Ole Paulsen, Physiological Laboratory, Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge CB2 3EG, United Kingdom, op210{at}cam.ac.uk
Author contributions
-
↵*O.A.S. and J.R.L. contributed equally to this work.
Disclosures
- Received May 22, 2010.
- Revision received October 27, 2010.
- Accepted November 16, 2010.
-
This work was supported by the Wellcome Trust and an equipment grant from the Alzheimer's Research Trust (funded by Doris Field Charitable Trust). O.A.S. holds a Wellcome Trust OXION studentship. E.M.T. is a Royal Society Research Fellow. F.D. held a Wellcome Trust Studentship in Neuroscience. R.W.-M. held a Wellcome Trust Research Career Development Fellowship, and the work was supported in part by CurePSP. M.V.-C. holds a Wellcome Trust OXION Training Fellowship. O.A.S., J.R.L., J.D., C.E.J.A., E.M.T. and M.V.-C. conducted experiments; H.N.D, M.P.V. and F.D. generated and maintained the Tau−/− mouse strain; O.A.S., J.R.L. and M.V.-C. analyzed the data. R.W.-M., O.P. and M.V.-C. designed the experiments. O.A.S., O.P. and M.V.-C. wrote the manuscript. All authors discussed the project and approved the final version of the manuscript.
- Correspondence should be addressed to either of the following: Dr. Mariana Vargas-Caballero, Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom, mariana.vargas{at}dpag.ox.ac.uk; or Prof. Ole Paulsen, Physiological Laboratory, Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge CB2 3EG, United Kingdom, op210{at}cam.ac.uk