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Articles, Behavioral/Systems/Cognitive

Auditory Cortex Encodes the Perceptual Interpretation of Ambiguous Sound

Niclas Kilian-Hütten, Giancarlo Valente, Jean Vroomen and Elia Formisano
Journal of Neuroscience 2 February 2011, 31 (5) 1715-1720; DOI: https://doi.org/10.1523/JNEUROSCI.4572-10.2011
Niclas Kilian-Hütten
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Giancarlo Valente
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Jean Vroomen
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Elia Formisano
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    Figure 1.

    Results of the auditory pretest. The mean proportions (p) of /aba/ classifications across the 11 participants for each stimulus in the nine-sound continuum are given. Sound 4 was chosen as A? for eight of the participants and sound 5 for the remaining three.

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    Figure 2.

    Schematic overview of the experimental procedure. Each run consisted of 10 mini-runs, which were each composed of a bimodal exposure block (A?Vd or A?Vb) and six auditory posttest trials. The bimodal blocks were presented within eight TRs, each of which entailed 1500 ms of scanning and 500 ms of video presentation. Between auditory posttest trials, fixation periods averaged six TRs.

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    Figure 3.

    a, Results of statistical univariate analysis. Overall auditory cortical activation in response to the ambiguous auditory stimuli as estimated with univariate random effects general linear model analysis (statistical parametric F map, group results of cortex-based aligned datasets, p < 1.7 × 10−11). The pairwise statistical comparison between the two perceptual conditions (/aba/ vs /ada/) did not yield significant results. b, Illustration of the anatomical masks used. Classification was anatomically confined to the temporal lobe. The exact boundaries of the anatomical masks were determined on a subject basis to account for individual differences in anatomy.

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    Figure 4.

    Classification accuracies for individual participants (identified by their initials). Accuracies obtained with the actual labels were significantly higher than the accuracies derived from the analysis using permuted class labels (p < 5.6 × 10−4). avrg, Average.

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    Figure 5.

    Discriminative map. Group map of the 30% of active voxels most discriminative for the purely perceptual difference between /aba/ and /ada/ (cortex-based aligned, smoothed). A location was color-coded if it was present on the individual maps of at least seven of the 11 subjects. This corresponds to a false discovery rate-corrected threshold of q = 2.75 × 10−3. Maps are overlaid on the reconstructions of the average hemispheres of the 11 subjects (top) and on inflated reconstructions of the right and left temporal lobes of these average hemispheres (bottom). RH, Right hemisphere; LH, left hemisphere; HG, Heschl's gyrus.

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The Journal of Neuroscience: 31 (5)
Journal of Neuroscience
Vol. 31, Issue 5
2 Feb 2011
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Auditory Cortex Encodes the Perceptual Interpretation of Ambiguous Sound
Niclas Kilian-Hütten, Giancarlo Valente, Jean Vroomen, Elia Formisano
Journal of Neuroscience 2 February 2011, 31 (5) 1715-1720; DOI: 10.1523/JNEUROSCI.4572-10.2011

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Auditory Cortex Encodes the Perceptual Interpretation of Ambiguous Sound
Niclas Kilian-Hütten, Giancarlo Valente, Jean Vroomen, Elia Formisano
Journal of Neuroscience 2 February 2011, 31 (5) 1715-1720; DOI: 10.1523/JNEUROSCI.4572-10.2011
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