Article Information
PubMed
Published By
History
- Received July 6, 2011
- Revision received October 24, 2011
- Accepted October 28, 2011
- First published January 4, 2012.
- Version of record published January 4, 2012.
Copyright & Usage
Copyright © 2012 the authors 0270-6474/12/320124-09$15.00/0
Author Information
- Gizem Donmez1,
- Anirudh Arun1,
- Chee-Yeun Chung3,
- Pamela J. McLean2,
- Susan Lindquist3, and
- Leonard Guarente1
- 1Paul F. Glenn Laboratory and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139,
- 2Department of Neurology, MassGeneral Institute for Neurodegenerative Disease, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, and
- 3Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142
Author contributions
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Author contributions: G.D. and L.G. designed research; G.D., A.A., C.-Y.C., and S.L. performed research; C.-Y.C., P.J.M., and S.L. contributed unpublished reagents/analytic tools; G.D. analyzed data; G.D. and L.G. wrote the paper.
Disclosures
- Received July 6, 2011.
- Revision received October 24, 2011.
- Accepted October 28, 2011.
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This work was supported by an American Parkinson Disease Association and Johnson & Johnson postdoctoral fellowships (G.D.), NIH Grant NS063963 (P.J.M.), HHMI Collaborative Innovation Award and a grant from the RJG Foundation (S.L.), and grants from the NIH and a gift from the Glenn Foundation for Medical Research (L.G.). We are grateful to Joseph Mazzuli for advice and help with A53T α-synuclein-expressing H4 cells. We thank Abdullah Yalcin for comments on this manuscript.
- Correspondence should be addressed to Leonard Guarente at the above address. leng{at}mit.edu
