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Featured ArticleArticles, Cellular/Molecular

Neurofibromin Modulates Adult Hippocampal Neurogenesis and Behavioral Effects of Antidepressants

Yun Li, Yanjiao Li, Renée M. McKay, Dieter Riethmacher and Luis F. Parada
Journal of Neuroscience 7 March 2012, 32 (10) 3529-3539; https://doi.org/10.1523/JNEUROSCI.3469-11.2012
Yun Li
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Yanjiao Li
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Renée M. McKay
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Dieter Riethmacher
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Luis F. Parada
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.3469-11.2012
PubMed 
22399775
Published By 
Society for Neuroscience
History 
  • Received July 7, 2011
  • Revision received January 11, 2012
  • Accepted January 12, 2012
  • First published March 7, 2012.
  • Version of record published March 7, 2012.
Copyright & Usage 
Copyright © 2012 the authors 0270-6474/12/323529-11$15.00/0

Author Information

  1. Yun Li1,
  2. Yanjiao Li1,
  3. Renée M. McKay1,
  4. Dieter Riethmacher2, and
  5. Luis F. Parada1
  1. 1Department of Developmental Biology and Kent Waldrep Center for Basic Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, and
  2. 2Development and Regeneration, Human Genetics Division, University of Southampton, Southampton, United Kingdom
View Full Text

Author contributions

  1. Author contributions: Yun Li and L.F.P. designed research; Yun Li and Yanjiao Li performed research; D.R. contributed unpublished reagents/analytic tools; Yun Li, R.M.M., and L.F.P. analyzed data; Yun Li, R.M.M., and L.F.P. wrote the paper.

Disclosures

    • Received July 7, 2011.
    • Revision received January 11, 2012.
    • Accepted January 12, 2012.
  • This work was supported by NINDS Grant R37NS033199 and NIMH Conte Center Grant P50MH66172. L.F.P. is an American Cancer Society Research Professor. We thank Shawna Kennedy, Linda McClellan, Steven McKinnon, Andrew Tyler, and Alvin Chandra for technical support, Drs. Jian Chen and Chang-Hyuk Kwon for assistance with the Nestin-CreERT2 mice, and members of the Parada laboratory for helpful suggestions. We thank Dr. Steven Kernie for insightful discussions.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to either Dr. Luis F. Parada, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9133, luis.parada{at}utsouthwestern.edu, or Dr. Yun Li, at her present address: Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, yli{at}wi.mit.edu

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Jan 20182193
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Total 202575290116
Total4151859668
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The Journal of Neuroscience: 32 (10)
Journal of Neuroscience
Vol. 32, Issue 10
7 Mar 2012
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Neurofibromin Modulates Adult Hippocampal Neurogenesis and Behavioral Effects of Antidepressants
Yun Li, Yanjiao Li, Renée M. McKay, Dieter Riethmacher, Luis F. Parada
Journal of Neuroscience 7 March 2012, 32 (10) 3529-3539; DOI: 10.1523/JNEUROSCI.3469-11.2012

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Neurofibromin Modulates Adult Hippocampal Neurogenesis and Behavioral Effects of Antidepressants
Yun Li, Yanjiao Li, Renée M. McKay, Dieter Riethmacher, Luis F. Parada
Journal of Neuroscience 7 March 2012, 32 (10) 3529-3539; DOI: 10.1523/JNEUROSCI.3469-11.2012
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