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Articles, Cellular/Molecular

Heterogeneous Nuclear Ribonucleoprotein K, an RNA-Binding Protein, Is Required for Optic Axon Regeneration in Xenopus laevis

Yuanyuan Liu, Hurong Yu, Sarah K. Deaton and Ben G. Szaro
Journal of Neuroscience 7 March 2012, 32 (10) 3563-3574; https://doi.org/10.1523/JNEUROSCI.5197-11.2012
Yuanyuan Liu
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Hurong Yu
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Sarah K. Deaton
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Ben G. Szaro
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.5197-11.2012
PubMed 
22399778
Published By 
Society for Neuroscience
History 
  • Received October 14, 2011
  • Revision received January 17, 2012
  • Accepted January 19, 2012
  • First published March 7, 2012.
  • Version of record published March 7, 2012.
Copyright & Usage 
Copyright © 2012 the authors 0270-6474/12/323563-12$15.00/0

Author Information

  1. Yuanyuan Liu1,*,
  2. Hurong Yu1,2,*,
  3. Sarah K. Deaton1, and
  4. Ben G. Szaro1
  1. 1Department of Biological Sciences and the Center for Neuroscience Research, University at Albany, State University of New York, Albany, NY 12222, and
  2. 2Department of Anatomy and Histoembryology, Shanghai Medical College, Fudan University, Shanghai 200032, People's Republic of China
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Author contributions

  1. Author contributions: Y.L., H.Y., and B.G.S. designed research; Y.L., H.Y., S.K.D., and B.G.S. performed research; Y.L., H.Y., and B.G.S. analyzed data; Y.L. and B.G.S. wrote the paper.

  2. ↵*Y.L. and H.Y. contributed equally to this work.

Disclosures

    • Received October 14, 2011.
    • Revision received January 17, 2012.
    • Accepted January 19, 2012.
  • Financial support came from the National Science Foundation (IOS 951043) and an American Heart Association predoctoral fellowship (Y.L.). We thank Drs. Itzhak Fischer (Drexel University) and Beatrice Cardinali (Istituto di Biologia Cellulare, Italy) for tau and Xenopus hnRNP E2 antibodies, respectively. We also thank Dr. Christine Gervasi for help with spawning and rearing Xenopus, Dr. Min-Ho Lee for providing access to critical equipment for polysomal profiling, Dr. Kurt M. Gibbs for providing sections of spinal cord-transected tadpole, and Gregory M. Szczepanski for his help with pilot experiments testing the effectiveness of morpholino injection. Chen Wang and Erica Hutchins made helpful editorial comments on this manuscript.

  • Correspondence should be addressed to Ben G. Szaro, Department of Biological Sciences, University at Albany, SUNY, 1400 Washington Avenue, Albany, NY 12222. bgs86{at}albany.edu

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Jan 201823411
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Oct 202031710
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Apr 20213144
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Aug 20251208
Sep 202583217
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Total 202550249120
Total3131734687
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The Journal of Neuroscience: 32 (10)
Journal of Neuroscience
Vol. 32, Issue 10
7 Mar 2012
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Heterogeneous Nuclear Ribonucleoprotein K, an RNA-Binding Protein, Is Required for Optic Axon Regeneration in Xenopus laevis
Yuanyuan Liu, Hurong Yu, Sarah K. Deaton, Ben G. Szaro
Journal of Neuroscience 7 March 2012, 32 (10) 3563-3574; DOI: 10.1523/JNEUROSCI.5197-11.2012

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Heterogeneous Nuclear Ribonucleoprotein K, an RNA-Binding Protein, Is Required for Optic Axon Regeneration in Xenopus laevis
Yuanyuan Liu, Hurong Yu, Sarah K. Deaton, Ben G. Szaro
Journal of Neuroscience 7 March 2012, 32 (10) 3563-3574; DOI: 10.1523/JNEUROSCI.5197-11.2012
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