Article Information
- Received October 3, 2011
- Revision received January 10, 2012
- Accepted January 31, 2012
- First published March 21, 2012.
- Version of record published March 21, 2012.
Author Information
- Lan Jing1,2,*,
- Xiang-Ping Chu3,*,
- Yu-Qing Jiang1,4,*,
- Daniel M. Collier5,
- Bin Wang6,
- Qian Jiang3,
- Peter M. Snyder5, and
- Xiang-Ming Zha1
- 1Department of Cell Biology and Neuroscience, University of South Alabama College of Medicine, Mobile, Alabama 36688,
- 2State Key Laboratory of New Drug & Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China,
- 3Departments of Basic Medical Science and Anesthesiology, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri 64108,
- 4Department of Urology, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, China,
- 5Departments of Internal Medicine and Molecular Physiology and Biophysics, University of Iowa, Iowa City, Iowa 52242, and
- 6Department of Mathematics and Statistics, University of South Alabama, Mobile, Alabama 36688
Author contributions
Author contributions: L.J., X.-P.C., Y.-Q.J., P.M.S., and X.-M.Z. designed research; L.J., X.-P.C., Y.-Q.J., D.M.C., Q.J., and X.-M.Z. performed research; L.J., X.-P.C., D.M.C., B.W., P.M.S., and X.-M.Z. analyzed data; L.J., X.-P.C., P.M.S., and X.-M.Z. wrote the paper.
↵*L.J., X.-P.C. and Y.-Q.J. contributed equally to this work.
Disclosures
- Received October 3, 2011.
- Revision received January 10, 2012.
- Accepted January 31, 2012.
This work was supported by grants from the National Institutes of Health (R21 Grant #DA031259), the American Heart Association (Grant #0735092N), and the University of Missouri Research Board (X.-P.C.); a fellowship grant from The Third Hospital of Hebei Medical University (Y.-Q.J.), National Institutes of Health Grant HL072256 (P.M.S.), and startup funds from University of South Alabama (X.-M.Z.). The Nikon A1 confocal microscope was funded by National Institutes of Health/American Recovery & Reinvestment Act Equipment Grant #S10RR027535. We thank Drs. Michael Welsh and John Wemmie for providing the ASIC1a−/− mice and the rabbit anti-ASIC1 antibody, Dr. Michel Lazdunski for the rat ASIC1a construct, and Dr. Steven Green for the Lck-GFP construct.
- Correspondence should be addressed to Xiang-Ming Zha, Department of Cell Biology and Neuroscience, University of South Alabama College of Medicine, 307 University Boulevard, MSB1201, Mobile, AL 36688. zha{at}jaguar1.usouthal.edu