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Articles, Behavioral/Systems/Cognitive

The Glucagon-Like Peptide 1 (GLP-1) Analogue, Exendin-4, Decreases the Rewarding Value of Food: A New Role for Mesolimbic GLP-1 Receptors

Suzanne L. Dickson, Rozita H. Shirazi, Caroline Hansson, Filip Bergquist, Hans Nissbrandt and Karolina P. Skibicka
Journal of Neuroscience 4 April 2012, 32 (14) 4812-4820; DOI: https://doi.org/10.1523/JNEUROSCI.6326-11.2012
Suzanne L. Dickson
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Rozita H. Shirazi
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Caroline Hansson
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Filip Bergquist
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Hans Nissbrandt
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Karolina P. Skibicka
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.6326-11.2012
PubMed 
22492036
Published By 
Society for Neuroscience
History 
  • Received December 20, 2011
  • Revision received February 14, 2012
  • Accepted February 15, 2012
  • First published April 4, 2012.
  • Version of record published April 4, 2012.
Copyright & Usage 
Copyright © 2012 the authors 0270-6474/12/324812-09$15.00/0 This article is freely available online through the J Neurosci Open Choice option.

Author Information

  1. Suzanne L. Dickson1,
  2. Rozita H. Shirazi1,
  3. Caroline Hansson1,
  4. Filip Bergquist2,
  5. Hans Nissbrandt2, and
  6. Karolina P. Skibicka1
  1. 1Departments of Physiology and
  2. 2Pharmacology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, SE-405 30 Gothenburg, Sweden
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Author contributions

  1. Author contributions: K.P.S. designed research; R.H.S., C.H., F.B., and K.P.S. performed research; H.N. and K.P.S. analyzed data; S.L.D. and K.P.S. wrote the paper.

Disclosures

    • Received December 20, 2011.
    • Revision received February 14, 2012.
    • Accepted February 15, 2012.
  • We thank the Swedish Research Council for Medicine (2011-3054 to K.P.S., 2009-S266 to S.L.D., 12208, 2009-2618), European Commission 7th Framework [FP7-HEALTH-2009-241592 (EurOCHIP), FP7-KBBE-2009-3-245009 (NeuroFAST), and FP7-KBBE-2010-4-266408 (Full4Health)], Forskning och Utvecklingsarbete/Avtal om Läkarutbildning och Forskning Göteborg (ALFGBG-138741), NovoNordisk Fonden and the Swedish Foundation for Strategic Research to Sahlgrenska Center for Cardiovascular and Metabolic Research (A305-188). We also thank Frida Larsson for her technical assistance.

  • The authors declare no competing financial interests.

  • Correspondence should be addressed to Dr. Karolina P. Skibicka, Department of Physiology/Endocrinology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Medicinaregatan 11, P.O. Box 434, SE-405 30 Gothenburg, Sweden. Karolina.Skibicka{at}neuro.gu.se

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The Journal of Neuroscience: 32 (14)
Journal of Neuroscience
Vol. 32, Issue 14
4 Apr 2012
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The Glucagon-Like Peptide 1 (GLP-1) Analogue, Exendin-4, Decreases the Rewarding Value of Food: A New Role for Mesolimbic GLP-1 Receptors
Suzanne L. Dickson, Rozita H. Shirazi, Caroline Hansson, Filip Bergquist, Hans Nissbrandt, Karolina P. Skibicka
Journal of Neuroscience 4 April 2012, 32 (14) 4812-4820; DOI: 10.1523/JNEUROSCI.6326-11.2012

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The Glucagon-Like Peptide 1 (GLP-1) Analogue, Exendin-4, Decreases the Rewarding Value of Food: A New Role for Mesolimbic GLP-1 Receptors
Suzanne L. Dickson, Rozita H. Shirazi, Caroline Hansson, Filip Bergquist, Hans Nissbrandt, Karolina P. Skibicka
Journal of Neuroscience 4 April 2012, 32 (14) 4812-4820; DOI: 10.1523/JNEUROSCI.6326-11.2012
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