Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
  • EDITORIAL BOARD
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
  • SUBSCRIBE

User menu

  • Log in
  • My Cart

Search

  • Advanced search
Journal of Neuroscience
  • Log in
  • My Cart
Journal of Neuroscience

Advanced Search

Submit a Manuscript
  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
  • EDITORIAL BOARD
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
  • SUBSCRIBE
PreviousNext
Correction

Correction: Arnold et al., Defective Retinal Vascular Endothelial Cell Development as a Consequence of Impaired Integrin αVβ8-Mediated Activation of Transforming Growth Factor-β

Journal of Neuroscience 11 April 2012, 32 (15) 5351; DOI: https://doi.org/10.1523/JNEUROSCI.0672-12.2012
  • Article
  • Info & Metrics
  • eLetters
  • PDF
Loading

In the article “Defective Retinal Vascular Endothelial Cell Development as a Consequence of Impaired Integrin αVβ8-Mediated Activation of Transforming Growth Factor-β” by Thomas D. Arnold, Gina M. Ferrero, Haiyan Qiu, Isabella T. Phan, Rosemary J. Akhurst, Eric J. Huang, and Louis F. Reichardt, which appeared on pages 1197–1206 of the January 25, 2012 issue, the α and β symbols were missing from Note added in proof. The corrected Note added in proof is listed below:

Note added in proof. A related paper was published recently after the submission of our revised manuscript (Hirota et al., 2011). Both papers used nestin-driven Cre expression to delete Itgb8 within the retinal precursor cells and observed similar retinal hemorrhagic phenotypes. Harada et al. (2011) report a deficit in tip cell filopodia density not observed in our study. The authors did not include a description of the abnormalities in vascular branch point density, coverage, or stability that were observed in our study. Both papers provide data that strongly supports a role of this integrin in development of the secondary (deep) vascular plexus. Hirota et al. (2011) did not examine the role in the outer versus inner deep vascular plexus. Retinal anti-TGFβ injection by Hirota et al. (2011) provided data complementary to ours on the role of TGFβ as a downstream effector of this integrin. The most important disagreement between our papers concerns the role of αVβ8 in retinal astrocytes versus Müller glia. Hirota et al. (2011) concluded that retinal astrocyte-expressed αVβ8 is required for normal retinal angiogenesis because they observed expression of this integrin in cultured retinal astrocytes. Our data indicates that nestin-Cre promotes efficient gene deletion in Müller glia, but not retinal astrocytes in vivo. We also observed expression of the β8 subunit in Müller glia, but not retinal astrocytes in vivo. Following astrocyte-specific, GFAP-Cre-mediated Itgb8 deletion in vivo, we did not detect retinal hemorrhage or significant abnormalities in vascular branching, coverage, or stability. It seems likely that the cultures examined by Hirota et al. (2011) contained Müller glia that mediated TGFβ activation.

Back to top

In this issue

The Journal of Neuroscience: 32 (15)
Journal of Neuroscience
Vol. 32, Issue 15
11 Apr 2012
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Advertising (PDF)
  • Ed Board (PDF)
Email

Thank you for sharing this Journal of Neuroscience article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Correction: Arnold et al., Defective Retinal Vascular Endothelial Cell Development as a Consequence of Impaired Integrin αVβ8-Mediated Activation of Transforming Growth Factor-β
(Your Name) has forwarded a page to you from Journal of Neuroscience
(Your Name) thought you would be interested in this article in Journal of Neuroscience.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Correction: Arnold et al., Defective Retinal Vascular Endothelial Cell Development as a Consequence of Impaired Integrin αVβ8-Mediated Activation of Transforming Growth Factor-β
Journal of Neuroscience 11 April 2012, 32 (15) 5351; DOI: 10.1523/JNEUROSCI.0672-12.2012

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Request Permissions
Share
Correction: Arnold et al., Defective Retinal Vascular Endothelial Cell Development as a Consequence of Impaired Integrin αVβ8-Mediated Activation of Transforming Growth Factor-β
Journal of Neuroscience 11 April 2012, 32 (15) 5351; DOI: 10.1523/JNEUROSCI.0672-12.2012
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
  • Info & Metrics
  • eLetters
  • PDF

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

  • Correction: Sequerra, Goyal et al., “NMDA Receptor Signaling Is Important for Neural Tube Formation and for Preventing Antiepileptic Drug-Induced Neural Tube Defects”
  • Correction: Darbelli et al., “Quaking Regulates Neurofascin 155 Expression for Myelin and Axoglial Junction Maintenance”
  • Correction: Personius et al., “Neuromuscular NMDA Receptors Modulate Developmental Synapse Elimination”
Show more CORRECTION
  • Home
  • Alerts
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Issue Archive
  • Collections

Information

  • For Authors
  • For Advertisers
  • For the Media
  • For Subscribers

About

  • About the Journal
  • Editorial Board
  • Privacy Policy
  • Contact
(JNeurosci logo)
(SfN logo)

Copyright © 2022 by the Society for Neuroscience.
JNeurosci Online ISSN: 1529-2401

The ideas and opinions expressed in JNeurosci do not necessarily reflect those of SfN or the JNeurosci Editorial Board. Publication of an advertisement or other product mention in JNeurosci should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in JNeurosci.