Article Information
- Received November 4, 2011
- Revision received February 12, 2012
- Accepted March 5, 2012
- First published April 25, 2012.
- Version of record published April 25, 2012.
Author Information
- Meredith N. Braskie1,
- Neda Jahanshad1,2,
- Jason L. Stein1,
- Marina Barysheva1,
- Kori Johnson4,6,
- Katie L. McMahon4,
- Greig I. de Zubicaray5,
- Nicholas G. Martin6,
- Margaret J. Wright6,
- John M. Ringman3,
- Arthur W. Toga1, and
- Paul M. Thompson1
- 1Laboratory of Neuro Imaging, Department of Neurology and
- 2Medical Imaging Informatics Group, Department of Radiology, University of California, Los Angeles (UCLA) School of Medicine, Los Angeles, California 90095,
- 3Mary S. Easton Center for Alzheimer's Disease Research, Department of Neurology, UCLA, Los Angeles, California 90095,
- 4Centre for Advanced Imaging and
- 5School of Psychology, University of Queensland, Brisbane, Queensland 4072, Australia, and
- 6Queensland Institute of Medical Research, Brisbane, Queensland 4029, Australia
Author contributions
Author contributions: M.N.B., N.J., J.L.S., M.B., K.J., K.L.M., G.I.d.Z., N.G.M., M.J.W., J.M.R., A.W.T., and P.M.T. designed research; K.J., K.L.M., G.I.d.Z., N.G.M., and M.J.W. performed research; M.N.B., N.J., J.L.S., M.B., and P.M.T. analyzed data; M.N.B., N.J., J.L.S., K.L.M., G.I.d.Z., N.G.M., M.J.W., J.M.R., A.W.T., and P.M.T. wrote the paper.
Disclosures
- Received November 4, 2011.
- Revision received February 12, 2012.
- Accepted March 5, 2012.
This study was supported by the National Institute of Child Health and Human Development (Grant R01 HD050735), and the National Health and Medical Research Council (NHMRC 486682), Australia. Genotyping was supported by the NHMRC (Grant 389875). Additional support was provided by NIH R01 Grants AG040060, EB008432, EB008281, and EB007813. M.N.B. was funded in part by the NIH (Grant P50 AG-16570) and by the UCLA Easton Consortium for Biomarker and Drug Discovery in Alzheimer's Disease. N.J. was funded in part by the NIH-National Library of Medicine (T15 LM07356). J.L.S. was also funded by the ARCS Foundation and the NIMH (F31MH087061). G.I.d.Z. is supported by an Australian Research Council (ARC) Future Fellowship (FT0991634). We thank the twins and siblings for their participation. In Brisbane, we thank Marlene Grace and Ann Eldridge for twin recruitment, Aiman Al Najjar and other radiographers for scanning, Kerrie McAloney and Daniel Park for research support, and staff in the Molecular Epidemiology Laboratory for DNA sample processing and preparation.
The authors declare no competing financial interests.
- Correspondence should be addressed to Dr. Paul Thompson, Laboratory of Neuro Imaging, Department of Neurology, UCLA School of Medicine, 635 Charles Young Drive South, Suite 225, Los Angeles, CA 90095-7334. thompson{at}loni.ucla.edu
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