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Articles, Behavioral/Systems/Cognitive

Laminarly Orthogonal Excitation of Fast-Spiking and Low-Threshold-Spiking Interneurons in Mouse Motor Cortex

Alfonso J. Apicella, Ian R. Wickersham, H. Sebastian Seung and Gordon M. G. Shepherd
Journal of Neuroscience 16 May 2012, 32 (20) 7021-7033; https://doi.org/10.1523/JNEUROSCI.0011-12.2012
Alfonso J. Apicella
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Ian R. Wickersham
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H. Sebastian Seung
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Gordon M. G. Shepherd
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0011-12.2012
PubMed 
22593070
Published By 
Society for Neuroscience
History 
  • Received January 2, 2012
  • Revision received March 27, 2012
  • Accepted April 4, 2012
  • First published May 16, 2012.
  • Version of record published May 16, 2012.
Copyright & Usage 
Copyright © 2012 the authors 0270-6474/12/327021-13$15.00/0

Author Information

  1. Alfonso J. Apicella1,
  2. Ian R. Wickersham2,
  3. H. Sebastian Seung2, and
  4. Gordon M. G. Shepherd1
  1. 1Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, and
  2. 2Howard Hughes Medical Institute and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139
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Author contributions

  1. Author contributions: A.J.A. and G.M.G.S. designed research; A.J.A. performed research; I.R.W. and H.S.S. contributed unpublished reagents/analytic tools; A.J.A. analyzed data; A.J.A., I.R.W., and G.M.G.S. wrote the paper.

Disclosures

    • Received January 2, 2012.
    • Revision received March 27, 2012.
    • Accepted April 4, 2012.
  • This work was supported by The Simons Foundation (G.M.G.S.), The Whitehall Foundation (G.M.G.S.), National Institute of Neurological Disorders and Stroke–National Institutes of Health Grant NS061963 (G.M.G.S.), and the Howard Hughes Medical Institute (I.R.W., H.S.S.). We thank T. Kiritani and B. Suter for valuable input, M. Scanziani for helpful discussions, and C. T. Anderson and P. L. Sheets for comments on this manuscript. We are grateful to K. Cosgrove, J. Lübke, and I. Marchionni for help with morphology.

  • Correspondence should be addressed to Dr. Gordon M. G. Shepherd, Morton 5-660, 303 East Chicago Avenue, Chicago, IL 60611. g-shepherd{at}northwestern.edu

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The Journal of Neuroscience: 32 (20)
Journal of Neuroscience
Vol. 32, Issue 20
16 May 2012
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Laminarly Orthogonal Excitation of Fast-Spiking and Low-Threshold-Spiking Interneurons in Mouse Motor Cortex
Alfonso J. Apicella, Ian R. Wickersham, H. Sebastian Seung, Gordon M. G. Shepherd
Journal of Neuroscience 16 May 2012, 32 (20) 7021-7033; DOI: 10.1523/JNEUROSCI.0011-12.2012

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Laminarly Orthogonal Excitation of Fast-Spiking and Low-Threshold-Spiking Interneurons in Mouse Motor Cortex
Alfonso J. Apicella, Ian R. Wickersham, H. Sebastian Seung, Gordon M. G. Shepherd
Journal of Neuroscience 16 May 2012, 32 (20) 7021-7033; DOI: 10.1523/JNEUROSCI.0011-12.2012
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