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Articles, Behavioral/Systems/Cognitive

In for a Penny, in for a Pound: Methylphenidate Reduces the Inhibitory Effect of High Stakes on Persistent Risky Choice

Daniel Campbell-Meiklejohn, Arndis Simonsen, Jørgen Scheel-Krüger, Victoria Wohlert, Trine Gjerløff, Chris D. Frith, Robert D. Rogers, Andreas Roepstorff and Arne Møller
Journal of Neuroscience 19 September 2012, 32 (38) 13032-13038; https://doi.org/10.1523/JNEUROSCI.0151-12.2012
Daniel Campbell-Meiklejohn
1Centre of Functionally Integrative Neuroscience, Aarhus University, 8000 Aarhus, Denmark,
2Center for Neural Science, New York University, New York 10003,
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Arndis Simonsen
1Centre of Functionally Integrative Neuroscience, Aarhus University, 8000 Aarhus, Denmark,
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Jørgen Scheel-Krüger
1Centre of Functionally Integrative Neuroscience, Aarhus University, 8000 Aarhus, Denmark,
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Victoria Wohlert
1Centre of Functionally Integrative Neuroscience, Aarhus University, 8000 Aarhus, Denmark,
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Trine Gjerløff
1Centre of Functionally Integrative Neuroscience, Aarhus University, 8000 Aarhus, Denmark,
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Chris D. Frith
1Centre of Functionally Integrative Neuroscience, Aarhus University, 8000 Aarhus, Denmark,
3Wellcome Trust Centre for Neuroimaging, University College London, London WC1N 3BG, United Kingdom,
4All Souls College, University of Oxford, Oxford OX1 4AL, United Kingdom,
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Robert D. Rogers
5Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, United Kingdom, and
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Andreas Roepstorff
1Centre of Functionally Integrative Neuroscience, Aarhus University, 8000 Aarhus, Denmark,
6Interacting Minds Centre, Aarhus University, 8000, Aarhus C, Denmark
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Arne Møller
1Centre of Functionally Integrative Neuroscience, Aarhus University, 8000 Aarhus, Denmark,
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.0151-12.2012
PubMed 
22993421
Published By 
Society for Neuroscience
History 
  • Received January 11, 2012
  • Revision received July 23, 2012
  • Accepted July 26, 2012
  • First published September 19, 2012.
  • Version of record published September 19, 2012.
Copyright & Usage 
Copyright © 2012 the authors 0270-6474/12/3213032-07$15.00/0

Author Information

  1. Daniel Campbell-Meiklejohn1,2,
  2. Arndis Simonsen1,
  3. Jørgen Scheel-Krüger1,
  4. Victoria Wohlert1,
  5. Trine Gjerløff1,
  6. Chris D. Frith1,3,4,
  7. Robert D. Rogers5,
  8. Andreas Roepstorff1,6, and
  9. Arne Møller1
  1. 1Centre of Functionally Integrative Neuroscience, Aarhus University, 8000 Aarhus, Denmark,
  2. 2Center for Neural Science, New York University, New York 10003,
  3. 3Wellcome Trust Centre for Neuroimaging, University College London, London WC1N 3BG, United Kingdom,
  4. 4All Souls College, University of Oxford, Oxford OX1 4AL, United Kingdom,
  5. 5Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, United Kingdom, and
  6. 6Interacting Minds Centre, Aarhus University, 8000, Aarhus C, Denmark
View Full Text

Author contributions

  1. Author contributions: D.C.-M., J.S.-K., C.D.F., A.R., and A.M. designed research; A.S., V.W., T.G., and A.M. performed research; D.C.-M. contributed unpublished reagents/analytic tools; D.C.-M. analyzed data; D.C.-M., C.D.F., and R.D.R. wrote the paper.

Disclosures

    • Received January 11, 2012.
    • Revision received July 23, 2012.
    • Accepted July 26, 2012.
  • This work was funded by a Danish Council for Strategic Research and the Danish Council for Independent Research Problem Gambling grant awarded to D.C.-M., a Danish National Research Foundation Niels Bohr Visiting Professorship to C.D.F., and the Danish Medical Research Council. We thank Dr. Bradley Doll for statistical analysis advice.

  • Correspondence should be addressed to Dr. Daniel Campbell-Meiklejohn, Center for Neural Science, New York University, 4 Washington Place, Room 809, New York, NY 10003. dan.cfin{at}gmail.com

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Jan 20183153
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May 2019161613
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Feb 20202168
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Jun 20208117
Jul 20202114
Aug 2020252
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Oct 202011122
Nov 2020161717
Dec 20205139
Total 20206814282
Jan 20212156
Feb 202114810
Mar 2021103116
Apr 2021173014
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Aug 20211298
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Jul 20254337
Aug 202587113
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Nov 2025688519
Dec 20253143
Total 2025181584133
Total6442692952
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The Journal of Neuroscience: 32 (38)
Journal of Neuroscience
Vol. 32, Issue 38
19 Sep 2012
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In for a Penny, in for a Pound: Methylphenidate Reduces the Inhibitory Effect of High Stakes on Persistent Risky Choice
Daniel Campbell-Meiklejohn, Arndis Simonsen, Jørgen Scheel-Krüger, Victoria Wohlert, Trine Gjerløff, Chris D. Frith, Robert D. Rogers, Andreas Roepstorff, Arne Møller
Journal of Neuroscience 19 September 2012, 32 (38) 13032-13038; DOI: 10.1523/JNEUROSCI.0151-12.2012

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In for a Penny, in for a Pound: Methylphenidate Reduces the Inhibitory Effect of High Stakes on Persistent Risky Choice
Daniel Campbell-Meiklejohn, Arndis Simonsen, Jørgen Scheel-Krüger, Victoria Wohlert, Trine Gjerløff, Chris D. Frith, Robert D. Rogers, Andreas Roepstorff, Arne Møller
Journal of Neuroscience 19 September 2012, 32 (38) 13032-13038; DOI: 10.1523/JNEUROSCI.0151-12.2012
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