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Brief Communications

Overcoming Motor “Forgetting” Through Reinforcement Of Learned Actions

Lior Shmuelof, Vincent S. Huang, Adrian M. Haith, Raymond J. Delnicki, Pietro Mazzoni and John W. Krakauer
Journal of Neuroscience 17 October 2012, 32 (42) 14617-14621a; https://doi.org/10.1523/JNEUROSCI.2184-12.2012
Lior Shmuelof
1Motor Performance Laboratory, The Neurological Institute, Columbia University, New York, New York 10032,
5Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel 76100
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Vincent S. Huang
1Motor Performance Laboratory, The Neurological Institute, Columbia University, New York, New York 10032,
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Adrian M. Haith
2Department of Neurology,
3Department of Biomedical Engineering, and
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Raymond J. Delnicki
1Motor Performance Laboratory, The Neurological Institute, Columbia University, New York, New York 10032,
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Pietro Mazzoni
1Motor Performance Laboratory, The Neurological Institute, Columbia University, New York, New York 10032,
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John W. Krakauer
2Department of Neurology,
4Department of Neuroscience, Johns Hopkins University, Baltimore, Maryland 21287, and
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2184-12.2012
PubMed 
23077047
Published By 
Society for Neuroscience
History 
  • Received May 7, 2012
  • Revision received July 16, 2012
  • Accepted August 24, 2012
  • First published October 17, 2012.
  • Version of record published October 17, 2012.
Copyright & Usage 
Copyright © 2012 the authors 0270-6474/12/3214617-05$15.00/0

Author Information

  1. Lior Shmuelof1,5,
  2. Vincent S. Huang1,
  3. Adrian M. Haith2,3,
  4. Raymond J. Delnicki1,
  5. Pietro Mazzoni1, and
  6. John W. Krakauer2,4
  1. 1Motor Performance Laboratory, The Neurological Institute, Columbia University, New York, New York 10032,
  2. 2Department of Neurology,
  3. 3Department of Biomedical Engineering, and
  4. 4Department of Neuroscience, Johns Hopkins University, Baltimore, Maryland 21287, and
  5. 5Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel 76100
View Full Text

Author contributions

  1. Author contributions: L.S., V.S.H., A.M.H., and J.W.K. designed research; L.S., V.S.H., and R.J.D. performed research; P.M. contributed unpublished reagents/analytic tools; L.S., A.M.H., and R.J.D. analyzed data; L.S., A.M.H., P.M., and J.W.K. wrote the paper.

Disclosures

    • Received May 7, 2012.
    • Revision received July 16, 2012.
    • Accepted August 24, 2012.
  • This research was supported by NIH Grant R01NS052804 (J.W.K., P.M.), the Machiah Foundation/Jewish Community Federation (L.S.), and the Parkinson's Disease Foundation (P.M.). We thank Tomoko Kitago and Juan Camilo Cortes for assistance in developing the paradigm and Robert S. Sainburg for sharing experiment-control software.

  • Correspondence should be addressed to either of the following: Dr. Lior Shmuelof, Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel 76100, Lior.Shmuelof{at}weizmann.ac.il; or Dr. John W. Krakauer, Departments of Neurology and Neuroscience, Johns Hopkins University, Baltimore, MD 21287, jkrakau1{at}jhmi.edu

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Feb 20251612628
Mar 202567027
Apr 202584422
May 202551710
Total 202544334109
Total79536401820
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The Journal of Neuroscience: 32 (42)
Journal of Neuroscience
Vol. 32, Issue 42
17 Oct 2012
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Overcoming Motor “Forgetting” Through Reinforcement Of Learned Actions
Lior Shmuelof, Vincent S. Huang, Adrian M. Haith, Raymond J. Delnicki, Pietro Mazzoni, John W. Krakauer
Journal of Neuroscience 17 October 2012, 32 (42) 14617-14621a; DOI: 10.1523/JNEUROSCI.2184-12.2012

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Overcoming Motor “Forgetting” Through Reinforcement Of Learned Actions
Lior Shmuelof, Vincent S. Huang, Adrian M. Haith, Raymond J. Delnicki, Pietro Mazzoni, John W. Krakauer
Journal of Neuroscience 17 October 2012, 32 (42) 14617-14621a; DOI: 10.1523/JNEUROSCI.2184-12.2012
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