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Intracisternal Interleukin-1 Receptor Antagonist Prevents Postoperative Cognitive Decline and Neuroinflammatory Response in Aged Rats

Ruth M. Barrientos, Amy M. Hein, Matthew G. Frank, Linda R. Watkins and Steven F. Maier
Journal of Neuroscience 17 October 2012, 32 (42) 14641-14648; https://doi.org/10.1523/JNEUROSCI.2173-12.2012

Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2173-12.2012
PubMed 
23077050
Published By 
Society for Neuroscience
History 
  • Received May 6, 2012
  • Revision received August 7, 2012
  • Accepted August 28, 2012
  • First published October 17, 2012.
  • Version of record published October 17, 2012.
Copyright & Usage 
Copyright © 2012 the authors 0270-6474/12/3214641-08$15.00/0

Author Information

  1. Ruth M. Barrientos,
  2. Amy M. Hein,
  3. Matthew G. Frank,
  4. Linda R. Watkins, and
  5. Steven F. Maier
  1. Department of Psychology and Neuroscience, Center for Neuroscience, University of Colorado at Boulder, Boulder, Colorado 80309

  • A. M. Hein's present address: Strategic Analysis, 4075 Wilson Boulevard, Suite 200, Arlington, VA 22203.

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Author contributions

  1. Author contributions: R.M.B., L.R.W., and S.F.M. designed research; R.M.B., A.M.H., and M.G.F. performed research; R.M.B. analyzed data; R.M.B. wrote the paper.

  • A. M. Hein's present address: Strategic Analysis, 4075 Wilson Boulevard, Suite 200, Arlington, VA 22203.

Disclosures

    • Received May 6, 2012.
    • Revision received August 7, 2012.
    • Accepted August 28, 2012.

  • This work was supported by National Institute on Aging Grant R01AG028271 (R.M.B., M.G.F., L.R.W., and S.F.M.).

  • Correspondence should be addressed to Dr. Ruth M. Barrientos, Department of Psychology and Neuroscience, Campus Box 345, University of Colorado at Boulder, Boulder, CO 80309-0345. ruth.barrientos{at}colorado.edu

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Total 20251124861
Total6513669909
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Intracisternal Interleukin-1 Receptor Antagonist Prevents Postoperative Cognitive Decline and Neuroinflammatory Response in Aged Rats
Ruth M. Barrientos, Amy M. Hein, Matthew G. Frank, Linda R. Watkins, Steven F. Maier
Journal of Neuroscience 17 October 2012, 32 (42) 14641-14648; DOI: 10.1523/JNEUROSCI.2173-12.2012
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