Article Information
- Received March 16, 2012
- Revision received August 14, 2012
- Accepted September 15, 2012
- First published November 14, 2012.
- Version of record published November 14, 2012.
Author Information
- Gabriela Plucińska1,2,*,
- Dominik Paquet3,4,*,
- Alexander Hruscha3,4,
- Leanne Godinho2,
- Christian Haass1,3,4,
- Bettina Schmid3,4,**, and
- Thomas Misgeld1,2,4,**
- 1Munich Cluster for Systems Neurology (SyNergy), 80802 Munich, Germany,
- 2Biomolecular Sensors, Center for Integrated Protein Sciences (Munich) at the Institute of Neuroscience and Institute for Advanced Study, Technische Universität München, 80802 Munich, Germany,
- 3Adolf-Butenandt-Institute, Biochemistry, Ludwig-Maximilians-University, 80336 Munich, Germany, and
- 4German Center for Neurodegenerative Diseases (DZNE), 80336 Munich, Germany
Author contributions
Author contributions: G.P., D.P., L.G., C.H., B.S., and T.M. designed research; G.P., D.P., A.H., and L.G. performed research; G.P., D.P., and L.G. contributed unpublished reagents/analytic tools; G.P. and D.P. analyzed data; G.P., D.P., L.G., C.H., B.S., and T.M. wrote the paper.
↵*G.P. and D.P. are equally contributing first authors.
↵**B.S. and T.M. are equally contributing senior authors.
Disclosures
- Received March 16, 2012.
- Revision received August 14, 2012.
- Accepted September 15, 2012.
This work was supported by the Sonderforschungsbereich “Molecular Mechanisms of Neurodegeneration” (SFB 596); the Center for Integrated Protein Sciences (Munich) and the European Community's Seventh Framework Programme (FP7/2007-2013) under Grant agreement no. 200611 (MEMOSAD). C.H. is supported by a research professorship at Ludwig-Maximilians-University. T.M. was supported by the Technische Universität München Institute of Advanced Studies, and the Alexander von Humboldt Foundation. G.P. was supported by the Graduate School of Technische Universität München (TUM-GS). We thank M. Teucke, D. Würzinger, and K. Wullimann for fish husbandry. We thank E.M. and E. Mandelkow for helpful discussions.
- Correspondence should be addressed to Thomas Misgeld, Chair for Biomolecular Sensors, Institute of Neuroscience, Technische Universität München and DZNE, Biedersteiner Strasse 29, 80802 Munich, Germany. thomas.misgeld{at}lrz.tu-muenchen.de