Article Information
- Received June 1, 2012
- Accepted September 17, 2012
- First published November 21, 2012.
- Version of record published November 21, 2012.
Author Information
- Yaosi Li1,
- Kerstin Seidel1,*,
- Peter Marschall1,*,
- Michael Klein1,
- Antonia Hope1,
- Jens Schacherl1,
- Jennifer Schmitz1,
- Mario Menk2,
- Jan H. Schefe3,
- Jana Reinemund1,
- Rebecca Hugel4,
- Peter Walden4,
- Andreas Schlosser9,
- Rudolf Volkmer5,
- Julia Schimkus6,
- Heike Kölsch10,
- Wolfgang Maier10,
- Johannes Kornhuber11,
- Lutz Frölich12,
- Sabrina Klare1,
- Sebastian Kirsch1,
- Kristin Schmerbach1,
- Sylvia Scheele1,
- Ulrike Grittner7,
- Frank Zollmann1,
- Petra Goldin-Lang1,
- Oliver Peters8,
- Ulrich Kintscher1,†,
- Thomas Unger1,†, and
- Heiko Funke-Kaiser1
- 1Center for Cardiovascular Research (CCR)/Institute of Pharmacology,
- 2Department of Anesthesiology and Intensive Care Medicine,
- 3Department of Hematology and Oncology,
- 4Department of Dermatology,
- 5Institute of Medical Immunology,
- 6Medical Outpatient Department,
- 7Department of Biometrics and Clinical Epidemiology, and
- 8Department of Psychiatry, Charité-Universitätsmedizin Berlin, 10115 Berlin, Germany;
- 9Center for Biological Systems Analysis (ZBSA), 79104 Freiburg, Germany;
- 10Department of Psychiatry, University Bonn, D-53012 Bonn, Germany;
- 11Department of Psychiatry, University Erlangen, 91054 Erlangen, Germany; and
- 12Central Institute of Mental Health, 68159 Mannheim, Germany
Author contributions
Author contributions: Y.L., P.M., F.Z., T.U., and H.F.-K. designed research; Y.L., K. Seidel, P.M., M.K., A.H., J. Schacherl, J. Schmitz, M.M., J.H.S., J.R., S. Klare, S. Kirsch, K. Schmerbach, and S.S. performed research; R.H., P.W., A.S., R.V., J. Schimkus, H.K., W.M., J.K., L.F., P.G.-L., O.P., and U.K. contributed unpublished reagents/analytic tools; Y.L., K. Seidel, P.M., J. Schmitz, J.H.S., U.G., P.G.-L., and H.F.-K. analyzed data; Y.L., F.Z., T.U., and H.F.-K. wrote the paper.
↵*K. Seidel and P.M. contributed equally to this work.
↵†U.K. and T.U. contributed equally to this work.
Disclosures
- Received June 1, 2012.
- Accepted September 17, 2012.
This work was supported by grants from the Deutsche Forschungsgemeinschaft to H.F.-K. (FU 463/2-1), the Dr. Werner Jackstädt Foundation (H.F.-K. and T.U.), and the German Federal Ministry of Education and Research to the German Dementia Competence Network (01GI0420). We thank Achim Kramer (Institute of Medical Immunology, Charité) for contributing personnel and equipment for the MS analyses and Dr. Christian Roos (Gene Bank of Primates, German Primate Center, Göttingen, Germany) for providing the chimpanzee DNA.
The authors declare no competing financial interests.
- Correspondence should be addressed to Heiko Funke-Kaiser, Center for Cardiovascular Research/Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Hessische Strasse 3-4, 10115 Berlin, Germany. heiko{at}funke-kaiser.com
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