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Articles, Behavioral/Systems/Cognitive

Episodic Reinstatement in the Medial Temporal Lobe

Bernhard P. Staresina, Richard N. A. Henson, Nikolaus Kriegeskorte and Arjen Alink
Journal of Neuroscience 12 December 2012, 32 (50) 18150-18156; DOI: https://doi.org/10.1523/JNEUROSCI.4156-12.2012
Bernhard P. Staresina
MRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, United Kingdom
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Richard N. A. Henson
MRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, United Kingdom
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Nikolaus Kriegeskorte
MRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, United Kingdom
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Arjen Alink
MRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, United Kingdom
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    Figure 1.

    a, Schematic of the experimental design, showing all four scenes and two exemplary trials at encoding (t1, t2) and retrieval (t1′, t2′) with two different memory outcomes. b, Illustration of the ERS analysis. ERS is the correlation between the activation pattern over voxels within a given region for a given trial at encoding and the activation pattern for the corresponding trial at retrieval (same-trial ERS, black diagonal cells). In our initial analysis, the difference in same-trial ERS for WS vs WO retrievals was assessed. In a subsequent analysis, same-trial ERS values were compared with the ERS between words that shared the same scene exemplar (same-scene ERS; gray, off-diagonal cells for example trial 2).

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    Figure 2.

    a, Structural scan of the first participant, showing the individual PhC (red) and HIPP (violet) masks. b, ERS for WS and WO retrievals in PhC and HIPP. Star, p < 0.05; ns, not significant (p > 0.1).

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    Figure 3.

    Left parahippocampal cortex cluster surviving small volume correction, displayed on the normalized anatomical scan averaged across participants.

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The Journal of Neuroscience: 32 (50)
Journal of Neuroscience
Vol. 32, Issue 50
12 Dec 2012
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Episodic Reinstatement in the Medial Temporal Lobe
Bernhard P. Staresina, Richard N. A. Henson, Nikolaus Kriegeskorte, Arjen Alink
Journal of Neuroscience 12 December 2012, 32 (50) 18150-18156; DOI: 10.1523/JNEUROSCI.4156-12.2012

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Episodic Reinstatement in the Medial Temporal Lobe
Bernhard P. Staresina, Richard N. A. Henson, Nikolaus Kriegeskorte, Arjen Alink
Journal of Neuroscience 12 December 2012, 32 (50) 18150-18156; DOI: 10.1523/JNEUROSCI.4156-12.2012
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