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When Up Is Down in 0g: How Gravity Sensing Affects the Timing of Interceptive Actions

Patrice Senot, Myrka Zago, Anne Le Séac'h, Mohammed Zaoui, Alain Berthoz, Francesco Lacquaniti and Joseph McIntyre
Journal of Neuroscience 8 February 2012, 32 (6) 1969-1973; https://doi.org/10.1523/JNEUROSCI.3886-11.2012
Patrice Senot
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Myrka Zago
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Anne Le Séac'h
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Mohammed Zaoui
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Alain Berthoz
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Francesco Lacquaniti
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Joseph McIntyre
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    Figure 1.

    Interception responses as a function of the ball's acceleration, direction of movement, and the gravitational context. a, Average trigger time with respect to the arrival of the ball (mean ± SEM). b, Average within-subject difference in trigger time between above and below (mean ± SEM) for subjects that performed the experiment in both gravity conditions. c, Success rate.

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    Figure 2.

    Results of control tests. a, Effect of performing the experiment in normal gravity either on the ground or in level flight of the aircraft (n.s.). b, Effect of performing the experiment on the ground with or without the influence of anti-nausea medication (n.s.).

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    Figure 3.

    Idealized otolith characteristics based on known physiological properties. a, Gravity profile for a 20 s upside-down handstand in normal Earth gravity (blue) and for a single cycle in parabolic flight (red). b, Fictive cell discharge rates for hypothetical saccular cells that are preferentially sensitive to upward (Z+) or downward (Z−) acceleration. c, Net gravitational estimate based on a simple subtraction of Z+ and Z− activities. Green shading highlights when the change from hypergravity to 0g might generate a net, transient signal consistent with negative acceleration.

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    Table 1.

    Results of ANOVA analyses

    EffectGravity as a group factorGravity as a repeated measure
    FSignificanceFSignificance
    Approach accelerationF(2,106) = 580.47p < 0.001F(2,34) = 333.78p < 0.001
    Approach durationF(2,106) = 26.47p < 0.001F(2,34) = 10.33p < 0.001
    Acceleration × durationF(4,212) = 33.45p < 0.001F(4,68) = 19.67p < 0.001
    DirectionF(1,53) = 7.68p < 0.01F(1,17) = 2.47n.s.
    GravityF(1,53) = 0n.s.F(1,17) = 0.84n.s.
    Direction × gravityF(1,53) = 23.45p < 0.001F(1,17) = 14.87p < 0.01
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The Journal of Neuroscience: 32 (6)
Journal of Neuroscience
Vol. 32, Issue 6
8 Feb 2012
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When Up Is Down in 0g: How Gravity Sensing Affects the Timing of Interceptive Actions
Patrice Senot, Myrka Zago, Anne Le Séac'h, Mohammed Zaoui, Alain Berthoz, Francesco Lacquaniti, Joseph McIntyre
Journal of Neuroscience 8 February 2012, 32 (6) 1969-1973; DOI: 10.1523/JNEUROSCI.3886-11.2012

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When Up Is Down in 0g: How Gravity Sensing Affects the Timing of Interceptive Actions
Patrice Senot, Myrka Zago, Anne Le Séac'h, Mohammed Zaoui, Alain Berthoz, Francesco Lacquaniti, Joseph McIntyre
Journal of Neuroscience 8 February 2012, 32 (6) 1969-1973; DOI: 10.1523/JNEUROSCI.3886-11.2012
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