Article Information
- Received July 25, 2011
- Revision received December 1, 2011
- Accepted December 16, 2011
- First published February 8, 2012.
- Version of record published February 8, 2012.
Author Information
Author contributions
Author contributions: B.E.D. and P.H.P. designed research; B.E.D. performed research; B.E.D. and P.H.P. analyzed data; B.E.D. and P.H.P. wrote the paper.
Disclosures
- Received July 25, 2011.
- Revision received December 1, 2011.
- Accepted December 16, 2011.
The authors declare no competing financial interests.
This work was supported by a fellowship to B.E.D. from the California Institute for Regenerative Medicine and by grants from the National Institute of Neurological Disorders and Stroke (NS045744 and ARRANS45744) and the McGrath Foundation. We thank Sylvian Bauer for thoughtful discussions and assistance initiating this study; Tania Banerji for technical assistance; Elaine Hsiao, Jan Ko, Natalia Malkova, and Puja Saluja for critical reading of this manuscript; and members of the California Institute of Technology Office of Laboratory Animal Resources, especially N. Miyamoto, for consistent excellent animal care. We also thank W. Muller and W. Richardson for the generous gifts of transgenic mouse lines.
- Correspondence should be addressed to Paul H. Patterson, Division of Biology M/C 216-76, California Institute of Technology, Pasadena, CA 91125. php{at}caltech.edu
