Figure 2. Modulation of unit activity in OFC and ACC. A—L, The normalized activity of OFC (A–F) and ACC (G–L) units before and after injection. Baseline activity is normalized to zero, and injection occurred at time = 0. Each row depicts an individual unit and units are sorted by direction and magnitude of change. The administered drug appears to the left of each row of color plots. Color scale for A–L appears at right. The total number of units (n) recorded from each rat (N), are listed below for each injection group. DOI 1.0, 3.0, 5.0 mg/kg; OFC: n = 97, 77, 91. N = 12, 11, 12. ACC: n = 27, 33, 36. N = 5, 6, 6. MK801 0.1 mg/kg; OFC: n = 91, N = 12. ACC: n = 24, N = 4. AMP 2.0 mg/kg; OFC: n = 86, N = 12. ACC: n = 27; N = 6. VEH control; OFC: n = 88, N = 11. ACC: n = 30, N = 4. Note that each drug group was associated with both increases and decreases in activity level.